Microbiological Profile of Ventilator Associated Pneumonia

Microbiological Profile of Ventilator Associated Pneumonia

  • Dr Shashikant Senior Resident, Department of Pediatrics, GIMS, Gadag, Karnataka.
  • Jayaraj Patil Assistant Professor, Department of Pediatrics, GIMS, Gadag, Karnataka.
Keywords: Ventilator Associated Pneumonia, Gram-Negative Bacteria, MRSA

Abstract

Background: Nosocomial gram negative bacterial pneumonias develop in hospitalized and are due to changes in the bacterial flora. Colonization of the upper respiratory tract by gram negative bacilli is mediated by alterations in the surface properties of the epithelial cells. In healthy individuals a film of fibronectin covers the epithelium lining the mucosa of the mouth and oropharynx and prevents the Gram-negative bacteria from adhering to the epithelial cells. This protective coating is lost in very ill individuals, so that pathogenic Gram- negative organisms adhere to receptors present on epithelial cells of the mucosa and soon colonize it. Subjects and Methods: The children aged between 1 month and 16 years who are included in this study are those who are on mechanical ventilator for more than 48 hours. All children  who are admitted in PICU and mechanically ventilated for more than 48 hours as per definition in inclusion criteria are investigated clinically, radiologically and bacteriologically to determine presence of pneumonia and isolate causative microorganism. Results: Common organism isolated ET tip culture of patients studied was Klebsiella 29 (19.3%), followed by Pseudomonas 6(4%), E.coli6 (4%), MRSA 6(4%). Most common organism isolated in urine culture of patients studied was E.coli 8(5.4%) followed by Klebsiella 3(2%). Conclusion: The common organisms isolated in blood culture and ET tip culture were Klebsiella, Pseudomonas aerogenosa and E. coli.

Published
2019-02-10
How to Cite
Shashikant, D., & Patil, J. (2019). Microbiological Profile of Ventilator Associated Pneumonia. Asian Journal of Clinical Pediatrics and Neonatology, 7(1), 1-4. Retrieved from https://aijournals.com/index.php/ajcpn/article/view/419