Asian Journal of Clinical Pediatrics and Neonatology <p><strong class="pull-left">Asian Journal of Clinical Pediatrics and Neonatology (AJCPN)</strong>&nbsp;&nbsp;is an open-access; freely accessible, online and print Quarterly peer-reviewed international journal publishes a wide spectrum of advanced research in different fields of pediatrics and neonatology, covering etiology, diagnosis, therapy and prognosis aspects. <br> <strong>Online ISSN: 2347-3363 | Print ISSN: 2347-3355</strong></p> en-US (Dr. Rohit Varshney) Thu, 16 May 2019 14:24:37 +0000 OJS 60 A Comparative Study of Pulse Oximetry Screening and Clinical Examination in Diagnosis of Congenital Heart Disease <p><strong>Background: </strong>Pulse oximetry is a reliable and non-invasive method for measuring oxygen saturation and has a rapid response. During the past several years pulse oximetry has gained wide spread use in the neonatal oxygen monitoring. The present study was done to determine if a pulse oximetry screening combined with clinical examination is superior in the diagnosis of congenital heart disease to clinical examination alone. <strong>Subjects and Methods: </strong>The term new-born babies born in NARAYANA medical college and Hospital during the study period of 12months (February 2018 to January 2019) had a thorough clinical examination on day 2 of life with emphasis on peripheral pulses, cyanosis, tachypnea, cardiac pulsations and murmurs. Pulse oximetry screening was done within 4hrs of birth and at 48-72hrs of life. Chest X-ray, ECG and Echocardiogram were done for those babies with either abnormal clinical examination or pulse oximetry reading.Clinical examination was done again 2 weeks after discharge. <strong>Results: </strong>Though routine clinical examination is effective in detection of congenital heart disease in new-borns, combining pulse oximetry and clinical examination after birth had a higher sensitivity for detection of congenital heart diseases in new-borns. <strong>Conclusion: </strong>Combining clinical examination and pulse oximetry can enhance the clinician’s ability to detect life-threatening congenital heart disease in a timely manner. This issue requires the formulation of national policy that will make screening for CCHD a priority.</p> Shaik Nazeer Ahmed ##submission.copyrightStatement## Thu, 16 May 2019 00:00:00 +0000 A Study on Outcome of Early Caffeine Administration in Very Preterm Neonates <p><strong>Background: </strong>Apnea intervals frequently occur in very preterm infants. Methylxanthenes stimulate breathing efforts and hence have been used for treating apnea of prematurity. Aim: to study the outcome of early caffeine administration in very preterm neonates. <strong>Subjects and Methods:</strong> The first (1st) group babies received early caffeine within 48 hours of life before developing apnea. The second group (2nd) group babies received caffeine late after 48 hours, after onset of apneic episode. <strong>Results:</strong> There was no significant difference in the number of episodes of apnea, bradycardia and hypoxemia. Also no significant difference in the incidence of Patent ductus arteriosus (PDA), Intra ventricular hemorrhage (IVH), Necrotizing enterocolitis (NEC), Retinopathy of prematurity (ROP) or Bronchopulmonary dysplsia (BPD). <strong>Conclusion:</strong> There was no significant difference noted in the number of episodes of apnea, bradycardia and hypoxemia in the group with early caffeine administratration compared to late caffeine administration.</p> Dr Basavaraj, Hareesh Sanikam, Pavan Pujar, Anjali R, Pushpalatha K ##submission.copyrightStatement## Thu, 16 May 2019 00:00:00 +0000 Clinicoetiological Study of Epilepsy in Children Presenting To Speciality Epilepsy Clinic at Tertiary Medical Hospital <p><strong>Background: </strong>Objectives: To identify the clinical &amp; etiological profile of children and the characteristics of seizures in them along with therapeutic response. <strong>Subjects and Methods: </strong>All patients who attended the Epilepsy Clinic &amp; fulfilled the selection criteria were enrolled in study. This is a descriptive study of 18 months &amp; involved analysis of records of the patients who came to specialty OPD. Three groups were formed accordingly - focal, generalized &amp; unknown onset with further etiological sub-divisions -Genetic, Structural/Metabolic, Immune, Infectious &amp; Unknown. <strong>Results: </strong>In all, 417 patients were studied. The distribution as per clinical presentation was- group I (generalized) 215(58.5%) - group II (focal) 154(36.9%), group III (unknown) 48(4.6%). The main etiologies were perinatal asphyxia (28.3%) NHBI (11.4%) in (structural-metabolic) sub group. In Genetic &amp; Infectious, Channelopathies (10.5%) &amp; Post Meningitis Sequelae (4.7%)were main etiology. 56.3% of the patient in group II were on more than 3 AEDs. 14.3% in group I were weaned of AEDs. 61.4% patients in group II were having neurodevelopmental Sequelae. EEG revealed abnormal activity in 30(6.2%) in group I &amp; 31(19.3%) in group II. Maximum patient with refractory epilepsy were seen in group III. <strong>Conclusion: </strong>To have a good management of epilepsy we need to have multi-dimensional classification of epilepsy based on both clinical &amp; etiological spectrum. Perinatal Asphyxia &amp; NHBI are one of the most common yet avertible etiologies.</p> Zankhana R. Parekh, Umesh Joshi, Nitish Vora, Aasheeta Shah ##submission.copyrightStatement## Thu, 16 May 2019 00:00:00 +0000