A Study on Correlation of Umbilical Cord Arterial Blood pH with Perinatal Asphyxia & Early Neonatal Outcome

Correlation of Umbilical Cord Arterial Blood pH with Perinatal Asphyxia

  • Nutan Singh Associate Professor, Department Of Paediatrics, Susheela Tiwari Hospital, Haldwani, Uttarakhand, India.
  • Asheesh Kumar Gupta Post Graduate Student, Department Of Paediatrics, Susheela Tiwari Hospital, Haldwani, Uttarakhand, India. https://orcid.org/0000-0001-6532-4776
  • Ajay Kumar Arya Professor, Department Of Paediatrics, Susheela Tiwari Hospital, Haldwani, Uttarakhand, India.
Keywords: pH, non-stress test, Apgar score, perinatal asphyxia

Abstract

Background: Perinatal asphyxia is one of the major causes of neonatal morbidity & mortality. Asphyxia can damage almost every organ of neonate. Our purpose was to determine the correlation of cord blood pH with birth asphyxia & early neonatal outcome. Subjects and Methods: A prospective study was conducted over a period of one year at STH Haldwani. We enrolled 108 term neonates with signs of fetal distress, thick MSL, non-reassuring NST & there were subjected for estimation of umbilical cord blood pH, APGAR score, outcome looked were resuscitation needed, NICU admission, delay in feed & encephalopathy (sarnat & sarnat stage). Results: In our study, cord blood pH had significant correlation with perinatal asphyxia(R=-0.926). Area under ROC curved showed that mean pH <7.1 (ROC=0.998) is very significant in predicting the adverse outcome. Conclusion: Cord blood pH is very sensitive and specific & has good correlation in predicting the birth asphyxia & adverse neonatal outcome. Measurement of cord blood pH is recommended in all the neonates with signs of fetal distress.

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References

Ghimire PR, Agho KE, Akombi BJ, Wali N, Dibley M, Raynes- Greenow C. Perinatal Mortality in South Asia: Systematic Review of Observational Studies. Int J Environ Res Public Health. 2018;15(7):1428. Available from: https://dx.doi.org/10.3390/ijerph15071428.

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Mousaahmedpour-Kacho Y, Hagshenas M, Akbarianrad Z. Bahram Sadat Nasseri& Ali Bijani. Short outcome of neonates born with abnormal umbilical cord arterial blood gases. Iran J Pediatr. 2015;25(3).

Published
2020-07-09
How to Cite
Singh, N., Gupta, A. K., & Arya, A. K. (2020). A Study on Correlation of Umbilical Cord Arterial Blood pH with Perinatal Asphyxia & Early Neonatal Outcome. Asian Journal of Clinical Pediatrics and Neonatology, 8(2), 30-35. https://doi.org/10.47009/ajcpn.2020.8.2.6