Assessment of lipid profile in CKD patients

Abstract

Background: To assess lipid profile in CKD patients. Methodology: Seventy CKD patients of both genders were selected. Group I had CKD patients and group II had equal age and gender matched healthy subjects. All were subjected to ultrasonography (USG). Assessment of blood urea, serum creatinine, lipid profile such as total cholesterol, triglycerides, HDLc, LDLc, VLDLc were done with semi-autoanalyzer. Results: There were 20 males and 15 females in group I and 18 males and 17 females in group II. The mean total cholesterol was 132.4 mg/dl in group I and 147.6 mg/dl in group II. TG was 150.6 mg/dl in group I and 96.8 mg/dl in group II. HDLc was 32.2 mg/dl in group I and 44.1 mg/dl in group II. LDLc was 64.1 mg/dl in group I and 76.2 mg/dl in group II. VLDLc was 32.4 mg/dl in group I and 18.6 mg/dl in group II. The difference was significant (P< 0.05). The mean blood urea was 126.1 mg/dl in group I and 30.4 mg/dl in group II. The mean serum creatinine was 6.4 mg/dl in group I and 0.98 mg/dl in group II. The difference was significant (P< 0.05). Conclusion: There was increased triglycerides, increased VLDL and reduced HDL in CKD patients leading to increased cardiovascular complications.