A Study on Clinical Proﬁle, Risk Factors, Angiographic Proﬁle and Short-Term Mortality of Acute Coronary Syndrome in Smokers vs Non Smokers

2020-07-07T01:35:11+00:00

Background: Smoking has long been positively associated with the development and progression of coronary heart disease. However, lon- gitudinal cohort studies evaluating smoking habits among cardiac patients as well as the role of socio-demographic factors determining such behaviours are scarce and have been focused on primary care practice Prevalence of acute coronary syndrome in young individuals is increasing progressively. Previous studies have focused on the analysis of risk factors and to some extent coronary angiographic profile in smokers vs non-smokers patients with acute coronary syndrome. Aims and objective: To study the acute coronary syndrome in smokers versus non-smokers and to analyse with respect to baseline characteristics. Subjects and Methods: It was a prospective study conducted at Department of Cardiology, Katuri Medical College & Hospital Guntur. Results: In the present study, Acute coronary syndrome occurred seven years earlier in smokers compared with non-smokers (p<0.05) Smokers were frequently male subjects compared with non-smokers (p<0.001) Smokers had a lower prevalence of Diabetes compared with non-smokers (p<0.001) Smokers had a higher prevalence of Obesity compared with non-smokers (p<0.001) Smokers presented with more Acute infarctions and less Unstable angina compared with non-smokers (P<0.001). Conclusion: In the present study, significant differences were observed in coronary risk factor profile between smokers and non-smokers patients with STEMI and NSTEMI/UA. Larger studies will be required to establish specific associations between presentation of acute coronary syndromes and angiographic profiles in smokers.

Clinical Study on Psychiatric Morbidity in Suicide Attempters- A Observational Study

2020-07-07T06:46:14+00:00

Background: Suicide is a tragic and serious preventable public health problem all over the world. It is one of the three leading causes of death globally. Usually suicide has no single cause. It is the endpoint of an individual process, in which several cultural, social, situational, psychological, and biological factors interact. Aims & Objective: The objective of the current study is to evaluate the nature of psychiatric morbidity and it’s severity in patients who have attempted suicide, its relation to the socio-demographic and clinical variables and the particulars of the current attempt. Subjects and Methods: Fifty patients with alleged history of suicide attempt were evaluated. Tools used were Socio Economic Status Schedule, Suicide Intent Scale and Comprehensive Psychopathology Rating Scale. ICD 10-AM Symptom Check List was used to evaluate and find out psychiatric diagnosis and final diagnosis was made on the basis of ICD-10- Classification of mental and behavioral disorders, Diagnostic Criteria for Research (DCR-10). Results: Most subjects are in the age group of 18-30, married, Hindus, with a primary education, semi-skilled workers with average monthly income of more than 3000 rupees from a nuclear family of semi urban area and belong to SESS category III. Adjustment disorder with brief depressive reaction is the most common diagnosis made and the diagnosis has statistically significant relation with past attempt, recent stressors, and motive. Type of attempt, method used, venue, lethality, and medical complication of the attempt have significant relation with, substance dependence and its total duration, gender, medication history and total duration of symptoms. Suicide intent score is statistically related with gender, total duration of symptoms, family history, motive, venue and lethality. Conclusion: Significant proportions of the individuals who attempt suicide have psychiatric morbidity. Attempted suicide can be considered to be a distinct sub- group of psychiatric symptoms which is usually neglected but is the most common cause of morbidity and mortality in subjects with psychiatric disorders. Patients who attempt suicide require special attention and management by all the medical professionals.

Asian Journal of Medical Research

A Study on Clinical Proﬁle, Risk Factors, Angiographic Proﬁle and Short-Term Mortality of Acute Coronary Syndrome in Smokers vs Non Smokers

Clinical Study on Psychiatric Morbidity in Suicide Attempters- A Observational Study