Study of Serum Amylase Levels in Patients with Type 2 Diabetes Mellitus in a Tertiary Care Hospital
Serum Amylase Levels in Patients with Type 2 Diabetes Mellitus
Abstract
Background: Diabetes mellitus is an endocrine disorder of the pancreas, due to inadequate synthesis of insulin and /or resistance to the action of it. There is a close anatomical and functional relationship between its endocrine and exocrine portions both directly and in directly. So we are studying the Serum amylase in Type2 Diabetes mellitus (DM). The aims and objective is to study the Serum Amylase levels in patients of Type-2 Diabetes Mellitus and to correlate Serum Amylase level with the HbA1c level in patients with type-2 DM. Subjects and Methods: Patients with Type-2 Diabetes Mellitus aged more than 30 years were taken for the study. After obtaining consent from patient, a detailed history was taken and a proper clinical examination was done. Relevant clinical investigations were done. Serum Amylase was measured. Then Serum Amylase level was compared with the HbA1c level. Results: In this study, serum amylase level was statistically significantly lower in Type 2 DM group compared to non diabetics group with p value <0.01. Conclusion: The study revealed that patients with Type 2 DM the exocrine functions of pancreas are also affected. Patients of Type 2 DM have low serum amylase levels. Serum amylase levels was negatively correlated with HbA1c levels in patients with type 2 DM, indicating the exocrine dysfunction which needs further evaluation to rule out chronic exocrine pancreatic insufficiency in type 2 DM patients .
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