A Study of Clinical and Laboratory Profile of Dengue Fever in Tertiary Centre

Clinical and Laboratory Profile of Dengue Fever

Abstract

Background: Dengue is an acute febrile disease in the tropical and subtropical regions. There is a steady rise in Dengue outbreaks in India. The present study describes clinical and laboratory findings of serologically confirmed hospitalized cases of dengue fever. Subjects and Methods: Prospective study was done in seropositive hospitalized adult patients in Muzaffarnagar Medical College, Muzaffarnagar, U.P. 84 patients were analyzed. Clinical features, Haematological and Biochemical parameters were noted. Results: Out of 84 patients studied, 51 were male and 33 were female. The fever was present in all patients, followed by Anorexia in 65 (77.38%), Vomiting in 56 (66.66%), Myalgia in 52 (61.90%), Headache in 37 (44.04%), Joint pain in 25 (29.76%), Retrobulbar pain in 24 (28.57%) and Rashes in 18 (21.42%) patients. Abdominal pain was present in 11 (13.09%), Hepatomegaly in 10 (11.90%), Pleural effusion in 6 (7.14%) and Ascites in 9 patients (10.71%). Shock was present in 5 (5.95%) and bleeding in 3 (3.57%) patients. Significant derangement in platelet count was noted. Conclusion: The problem of Dengue fever is on continuous rise. It may be due to huge population, poor sanitation, waste management policies, lack of medical facilities in the rural population and inadequate mosquito control. So, a continuous sero-epidemiological surveillance, early diagnosis, timely and proper fluid management can reduce its complications, outbreaks and mortality.