Evaluation and Comparison of IMRT versus 3DCRT for Post-Mastectomy Chest Wall Irradiation
Evaluation and Comparison of IMRT versus 3DCRT
Background: Breast cancer is the most common cancer in females worldwide. Hence, we planned the present study to evaluate and compare IMRT and 3DCRT for post-mastectomy chest wall irradiation. Subjects and Methods: A total of 30 subjects were included in the present study. Adjuvant radiotherapy was planned in all the subjects to the chest wall. A Lead marker was used for marking the scar sites, drain sites and breast borders. Non-contrast computed tomography (CT) simulation and treatment was carried out in all the patients. Generation of Planning Target Volume (PTV) was done followed by contouring of organs at risk (OAR). 15 subjects were treated with three-dimensional conformal radiation therapy (3DCRT) and 15 subjects were with intensity-modulated radiation therapy (IMRT) for post-mastectomy radiotherapy (PMRT). Calculation of conformity index (CI) was done as per criteria previously described in the literature. Calculation of mean dose volume of ipsilateral lung and heart was done. All the results were summarized and analysed by SPSS software. Results: Significant results were obtained while comparing the Dmean (Gy) for heart and lungs in between the 3DCRT group and the IMRT group. Conclusion: In comparison to 3DCRT, among post-mastectomy left sided breast cancer patients, IMRT offered significant reduction in the dose volume of the ipsilateral lung and heart.