Study on Association between HbA1c and Lipid profile in Type 2 Diabetic Patients: A Teaching Hospital Based Study

Study on Association between HbA1c and Lipid profile in Type 2 Diabetic Patients

  • Pallavi Anand Associate professor, Department of Biochemistry, Rama Medical College Hospital and Research Centre, Rama City, Mandhana, Kanpur, Uttar Pradesh 209217.
  • Niranjan Shah Ph.D. Scholar, Department of Biochemistry, Rama Medical College Hospital and Research Centre, Rama City, Mandhana, Kanpur, Uttar Pradesh 209217.
  • Dr Shrawan Professor, Department of Medicine, Rama Medical College Hospital and Research Centre, Rama City, Mandhana, Kanpur, Uttar Pradesh 209217.
  • Uday Narayan Singh Professor & Head, Department of Biochemistry, Rama Medical College Hospital and Research Centre, Rama City, Mandhana, Kanpur, Uttar Pradesh 209217.
  • P. atayanarayana Professor and Dean, Department of Biochemistry, Rama Medical College Hospital and Research Centre, Rama City, Mandhana, Kanpur, Uttar Pradesh 209217.
Keywords: Type-2 DM, FBS, HbA1c and Lipid parameters

Abstract

Background: Diabetes mellitus is characterized by chronic hyperglycaemia with disturbances in carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. Subjects and Methods:  type 2 diabetic patients (Age range of 25-70 years) with an age & sex matched along with 50 healthy controls were selected as per the inclusion and exclusion criteria. Results: The mean age (Mean ± SD) of cases and controls were 48.6±13.42 and 30.9±10.23 years and mean BMI 21.38±4.2 & 25.2±1.83 respectively [Table-1]. The Mean ± SD of cases and controls were FBS (134.62 ± 20.2), HbA1c (7.8 ± 2.42), TC (155.6±31.7), TG (152.3±26.04), HDL-C (43.4 ± 8.07) and LDL-C (81.78 ± 36.8) and FBS (104 ± 12.06), HbA1c (5.1 ± 1.4), TC (142.6±2.5), TG (112.5±20.3), HDL-C (49.6 ± 9.5) and LDL-C (104.06 ± 17.15) respectively[Table-1]. In this study, the level of FBS, HbA1c, TC, TG, LDL-c, were significantly increased (P<0.05) while HDL-c level was significantly decreased (P<0.05) as compare to controls. Conclusion: HbA1c showed positive correlation with TC, TG, & LDL-c and negative correlations were observed between HbA1C and HDL-c.

Published
2019-03-31
How to Cite
Anand, P., Shah, N., Shrawan, D., Singh, U., & atayanarayana, P. (2019). Study on Association between HbA1c and Lipid profile in Type 2 Diabetic Patients: A Teaching Hospital Based Study. Asian Journal of Medical Research, 8(1), BC17-BC19. Retrieved from https://aijournals.com/index.php/ajmr/article/view/570
Section
Biochemistry