Correlation between hs-CRP, HbA1c and Oxidative Stress in Type-2 Diabetic Patients.
Correlation between hs-CRP, HbA1c and Oxidative Stress in Type-2 Diabetic Patients
Background: Diabetes mellitus is a collection of common metabolic disorder mainly considered by hyperglycaemia which results commencing from defective insulin secretion or insulin action or both. Subjects and Methods: 50 Type 2 Diabetic patients and 50 non diabetic subjects between the age group of 30-65 years who were all attending in OPD at Santosh Medical college and Hospital Ghaziabad, were selected for the study. All the patients were included as cases evaluated and diagnosed as Type 2 Diabetes mellitus on the basis of history and Biochemical investigations. Results: Significant positive correlation with a p value <0.000 was found between fasting blood glucose (FBS), postprandial blood glucose (PPBS) and hs-CRP level. Similarly, statistically significant positive correlation (p value<0.000) was also found between Glycosylated hemoglobin (HbA1c) and hs-CRP in the study group. Conclusion: There is strong association found between fasting & postprandial serum glucose, high-sensitivity C-reactive protein and glycated haemoglobin, MDA & Thiols.