Assessment of Surgical and Perioperative Outcomes of Elective Laparoscopic Cholecystectomy Under Spinal Compared with General Anaesthesia: A Randomized Controlled Trial

Surgical and Perioperative Outcomes of Elective Laparoscopic Cholecystectomy

  • Dev Kumar Saini Senior Resident, Department of General Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, Uttar Pradesh, India.
  • Khushi Gandhi Junior Resident, Department of General Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, Uttar Pradesh, India.
  • Ankur Singh Assistant Professor, Department of General Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, Uttar Pradesh, India.
  • Siddhant Jain Junior Resident, Department of General Surgery, Teerthanker Mahaveer Medical College and Research Center, Moradabad, Uttar Pradesh, India.
Keywords: Laparoscopic cholecystectomy, Spinal anaesthesia, General anaesthesia

Abstract

Background: Laparoscopic cholecystectomy (LC) is the gold standard for symptomatic cholelithiasis. Conventionally done under general anaesthesia (GA) for safe airway control and pneumoperitoneum tolerance, GA can cause postoperative nausea, vomiting, and delayed bowel recovery. Spinal anaesthesia (SA) is emerging as a safe, feasible alternative that avoids airway instrumentation and offers better postoperative pain relief and faster recovery. This study aims to compare surgical parameters in elective LC under spinal versus general anaesthesia. Subjects and Methods: This prospective randomized study enrolled 106 patients equally divided into SA and GA groups. Surgical parameters, intraoperative events, postoperative complications, pain scores, bowel function, and patient and surgeon satisfaction were compared. Results: The SA group showed lower early pain scores, faster bowel recovery, less nausea and vomiting, and similar operative times. Minor hypotension and bradycardia were manageable; conversion to GA was rare. Conclusion: SA is safe, feasible, cost-effective, and suitable for selected LC cases.

Downloads

Download data is not yet available.

References

1. Cunningham AJ, Brull SJ. Laparoscopic cholecystectomy: anesthetic implications. Anesth Analg. 1993;76:1120–33.
2. Turkstani A, Ibraheim O, Khairy G, Alseif A, Khalil N. Spinal versus general anesthesia for laparoscopic cholecystectomy a comparative study of cost effectiveness and side effects. Anaesth Pain & Intensive Care. 2009;13:9–14.
3. Sharp JR, Pierson WP, Brady CE. Comparison of CO2 and N2O-induced discomfort during peritoneoscopy under local anaesthesia. Gastroenterology. 1982;82:453–6.
4. Tiwari S, Chauhan A, Chaterjee P, Alam MT. Laparoscopic cholecystectomy under spinal anaesthesia: A prospective, randomised study. J Minim Access Surg. 2013 Apr;9(2):65-71. doi: 10.4103/0972-9941.110965. PMID: 23741111; PMCID: PMC3673576.
5. Gramatica L, Jr, Brasesco OE, Luna MA, Martinessi V, Panebianco G, Labaque F, et al. Laparoscopic cholecystectomy performed under regional anaesthesia in patients with obstructive pulmonary disease. Surg Endosc. 2002;16:472–5.
6. Hirvonen EA, Poikolainen EO, Pääkkönen ME, Nuutinen LS. The adverse hemodynamic effects of anesthesia, head-up tilt, and carbon dioxide pneumoperitoneum during laparoscopic cholecystectomy. Surg Endosc. 2004;14:272–7.
7. Ciofolo MJ, Clergue F, Seebacher J, Lefebvre G, Viars P. Ventilatory effects of laparoscopy under epidural anesthesia. Anesth Analg. 1990;70:357–61.
8. Longo MA, Cavalheiro BT, de Oliveira Filho GR. Laparoscopic cholecystectomy under neuraxial anesthesia compared with general anesthesia: Systematic review and meta-analyses. J Clin Anesth. 2017;41:48–54.
9. Kehlet H. Effect of postoperative pain treatment on outcome-current status and future strategies. Langenbecks Arch Surg. 2004;389:244–9.
10. Luchetti M, Palomba R, Sica G, Massa G, Tufano R. Effectiveness and safety of combined epidural and general anesthesia for laparoscopic cholecystectomy. Reg Anesth. 1996;21:465–9.
11. Johnson A. Laparoscopic surgery. Lancet. 1997;349(9052):631–5.
12. Crabtree JH, Fishman A, Huen IT. Videolaparoscopic peritoneal dialysis catheter implant and rescue procedures under local anesthesia with nitrous oxide pneumoperitoneum. Adv Perit Dial. 1998;14:83–6.
13. Kapoor T, Wrenn SM, Callas PW, Abu-Jaish W. Cost Analysis and Supply Utilization of Laparoscopic Cholecystectomy. Minim Invasive Surg. 2018;2018:7838103.
14. Strasberg SM. Tokyo Guidelines for the Diagnosis of Acute Cholecystitis. J Am Coll Surg. 2018 Dec;227(6):624.
15. Kose SH, Grice K, Orsi WD, Ballal M, Coolen MJL. Metagenomics of pigmented and cholesterol gallstones: the putative role of bacteria. Sci Rep. 2018 Jul 25;8(1):11218.
Published
2026-03-30
How to Cite
Saini, D. K., Gandhi, K., Singh, A., & Jain, S. (2026). Assessment of Surgical and Perioperative Outcomes of Elective Laparoscopic Cholecystectomy Under Spinal Compared with General Anaesthesia: A Randomized Controlled Trial. Asian Journal of Medical Research, 15(1), 1-4. Retrieved from https://aijournals.com/index.php/ajmr/article/view/2719