Assessment of Ferritin Deficiency in Patients with Heart Failure

Ferritin Deficiency in Patients with Heart Failure

Abstract

Background: To assess ferritin deficiency in patients with heart failure. Subjects and Methods: Eighty six chronic heart failure patients of either gender were selected and based on iron status, group I and II were formed. Group I had iron deficiency patients and group II were without it. Prospective, observational study was done. Parameters such as ferritin, serum iron, and transferrin saturation (TSAT) were measured. Results: Out of 86 patients, males comprised of 50 and females 36. Group I comprise of 20 males and 23 females and group II 18 males and 25 females. The difference was non- significant (P>0.05). The mean hemoglobin in group I patients was 11.6 g/dl and in group II was 13.2 g/dl. Iron level was 57.8 g/L and 97.5 g/L, MCV was 82.1 fl and 91.6 fl, TSAT was 13.1% and 28.5% and ferritin was 76.4 g/L and 262.1 g/L respectively. The difference in ferritin level was significant (P<0.05). Conclusion: Serum ferritin was significantly reduced in chronic heart failure patients. Anaemia is common comorbid condition in patients of heart failure.