Determination of Clinical Profile of Patients with Thrombocytopenia

Abstract

Background: To determine clinical profile of patients with thrombocytopenia. Subjects and Methods: 96 patients of fever with thrombocytopenia of either gender was selected. Parameters such as etiology, clinical data and site of bleeding and treatment outcome was recorded. Results: Out of 96 patients, males comprise 56 and females 40. Etiology was malaria in 22, viral fever in 20, dengue fever in 32, scrub typhus in 10, septicaemia in 6 and leptospirosis in 6 cases. Clinical symptoms were fever in 96, cough in 62, headache in 54, rashes in 34, pallor in 51, chills & rigors in 32, jaundice in 26 and bleeding in 15 patients.  Bleeding site was gum bleeding was seen in 8, bleeding per vagina in 1, Malena in 2, hematemesis in 2, hematuria in 1 and epistaxis in 1 patient. The difference was significant (P< 0.05). Conclusion: Most common cause of thrombocytopenia was malaria, viral fever, dengue fever, scrub typhus, septicaemia and leptospirosis. Most of the patients with platelets count less than 20000 needed blood transfusion.