Assessment of Renal Arterial Resistive Index in Type 2 Diabetic Nephropathy Patients

Renal Arterial Resistive Index in Type 2 Diabetic Nephropathy Patients

Abstract

Background: To assess renal arterial resistive index in type 2 diabetic nephropathy patients. Subjects and Methods: One hundred thirty type II diabetes mellitus patients with the diabetic nephropathy were selected and parameters such as blood pressure, glycosylated hemoglobin, serum creatinine, albuminuria, and 24-hour urine were recorded. Intrarenal resistive index was measured. Results: Stage 1 diabetic nephropathy comprises of 36 patients, stage 2 had 24, stage 3 had 52 and stage 4 had 18 patients. The difference was non- significant (P> 0.05). The mean systolic blood pressure (SBP) in stage 1 was 134.2 mm Hg and diastolic blood pressure (DBP) was 64.8 mm Hg, in stage 2 was 122.6 mm Hg and DBP was 62.4 mm Hg, in stage 3 was 140.8 mm Hg and DBP was 72.0 mm Hg and in stage 4 was 156.2 mm Hg and DBP was 94.6 mm Hg. The difference was significant (P<0.05). The mean RI in stage 1 patients was 0.610.02, in stage 2 was 0.680.04, in stage 3 was 0.740.05 and in stage 4 was 0.870.03. The difference was significant (P<0.05). There was positive correlation of RI with SBP (r- 0.52, p- 0.05), GFR (r- -0.02, p- 0.001) and albumin excreted in 24 hours urine (r- 0..03, p- 0.04). Conclusion: Increased systolic blood pressure, albumin excretion and severity of disease were capable of increasing RI values in diabetic nephropathy patients.