Sebaceoma in a 58 Years old Male Diagnosed on Cytology and Confirmed on Biopsy- A Case Report

Sebaceoma in a 58 Years old Male Diagnosed on Cytology and Confirmed on Biopsy

Abstract

Background: Sebaceoma is a benign adnexal tumor that usually presents as a yellowish nodule or plaque, most commonly seen in the head and neck region.  The occurence of sebaceoma has been associated with MuirTorre syndrome which is an autosomal dominant disorder and predisposes to other visceral malignancies. Case Report: We hereby, report a case of Sebaceoma involving the left axillary region in a 58 yrs old male. FNAC smears were hypercellular showing many clusters of basaloid cells, few showing anisonucleosis along with scattered cells of sebaceous differentiation, having vacuolated cytoplasm. The provisional diagnosis of Sebaceoma was suggested on cytology. These features were later confirmed by histopathological sections showing small, monomorphous basaloid cells admixed with cells showing sebaceous differentiation, having vacuolated cytoplasm and scalloped nuclei. We have attempted to review the literature on Sebaceoma and emphasized on its differential diagnoses, particularly sebaceous carcinoma and basal cell carcinoma with sebaceous differentiation. Conclusion: Sebaceoma is a rarely reported tumour and its diagnosis on cytology is way more challenging. Awareness of the cytological features of Sebaceoma will help in early specific diagnosis of this tumor at the time of aspiration, rather than a blanket term of benign adnexal tumour . Also, its association with MuirTorre syndrome, warrants its correct and timely identification and thus, genetic testing and surveillance for its other syndromic associations.