Assessment of Efficacy & Safety of Topical Eberconazole and Terbinafine in Patients of Tinea Versicolor

Topical Eberconazole and Terbinafine in Patients of Tinea Versicolor

Abstract

Background: To compare the safety & efficacy of Eberconazole and Terbinafine in patients of Tinea Versicolor. Subjects and Methods: 100 patients (58 males & 42 females) were selected and they were divided into two study groups. Group I patients were prescribed Terbinafine 1% cream for 15days and group II received Eberconazole 1% cream for15 days. Global clinical response assessment and visual analog scale was recorded in both groups. Results: There were 30 males and 22 females in group I and 28 males and 20 females in group II. in group I, 44 (88%) and in group II 39 (78%) showed complete healing. Mild residual disease was seen among 6 (12%) in group I and 10 (20%) in group II. Considerable residual disease was seen in 1 (2%) in group II only. A significant difference was observed between both groups (P< 0.05). The mean VAS score on baseline was 6.4 in group I and 7.0 in group II, on 7th day was 4.3 in group I and 5.4 in group II and on 15th day was 2.1 in group I and 2.9 in group II. Intergroup comparison showed non- significant difference (P> 0.05).  Conclusion: Both Eberconazole & Terbinafine drugs were effective in management of cases of Tinea Versicolor. Eberconazole, a newer azole can be a new addition in the armamentarium for the treatment of tinea versicolor.