A Comparative Study of Intravenous Norepinephrine and Mephentermine for Maintenance of Blood Pressure During Spinal Anesthesia for Caesarean Section:

Gagan Deep  Singh; Atanu  Mukherjee; Deepika  Bagga

Gagan Deep Singh Associate Professor, Department of Anesthesia, Muza?arnagar Medical College, Muza?arnagar, Uttar Pradesh, India
Atanu Mukherjee Associate Professor, Department of Anesthesia, Muza?arnagar Medical College, Muza?arnagar, Uttar Pradesh, India https://orcid.org/0000-0003-0474-1191
Deepika Bagga Final year MD Student, Department of Anesthesia, Muza?arnagar Medical College, Muza?arnagar, Uttar Pradesh, India

Keywords: Caesarean Section, Mephentermine, Norepinephrine, Spinal Anesthesia

Abstract

Background: To compare intravenous norepinephrine and mephentermine for maintenance of blood pressure during spinal anesthesia for cae- sarean section. Subjects and Methods: Our randomized study conducted among ninety- two subjects of American Society of Anaesthesiologists physical status (ASA)II and singleton term pregnancy posted for elective caesarean section. Subjects were randomized into 2 groups of ratio of 1:1. Group norepinephrine (N) received 8g intravenous norepinephrine and group mephentermine (M) received 6mg mephentermine. Results: A non- significant difference in systolic blood pressure at different intervals of time was observed between group N and M (P> 0.05). A non- significant difference in diastolic blood pressure at different intervals of time was observed between group N and M (P> 0.05). Adverse events recorded were nausea/vomiting in 8 in group N and 9 in group M, headache in 10 in group N and 11 in group M, shivering in 5 in group N and 4 in group M and hypertension 1 in group N. A non- significant difference was observed between two groups (P> 0.05). Conclusion: Intravenous norepinephrine is better than mephentermine in terms of controlling blood pressure.

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