Evaluation of Clinical Profile of Bipolar and Unipolar Depression Patients- A Clinical Study
Bipolar and Unipolar Depression.
Abstract
Background: The present study was conducted to assess the clinical profile of unipolar and bipolar depressive patients. Subjects & Methods: 74 patients diagnosed with unipolar (40) and bipolar (34) depressive disorders were selected. Depressive cognitions, catatonic features, suicidal thoughts, anhedonia, pseudodementia, dissociative features, panic attacks, delusions, first-rank symptoms, auditory hallucinations, and affective reactivity were recorded. Results: Out of 74 patients, males were 32 and females were 42. Age of onset was 32.2 years in group I and 20.4 years in group II, total duration was 12.4 years in group I and 16.2 years in group II, the number of episodes was 3.4 and 7.1 in group II, the number of hospitalizations was 2.8 in group I and 5.2 in group II, suicidal thoughts were seen in 21 in group I and 24 in group II, anhedonia 10 in group I and 23 in group II, psuedodementia 7 in group I and 13 in group II, dissociative features were seen in 11 in group I and 27 in group II, delusions 4 in group I and 8 in group II, panic symptoms 10 in group I and 18 in group II and auditory hallucination 7 in group I and 18 in group II. The difference was significant (P< 0.05). Conclusion: Authors found that common clinical features were suicidal thoughts, dissociative features, and anhedonia.
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References
Sharma V, Khan M, Smith A. A closer look at treatment resistant depression: is it due to a bipolar diathesis? J Affect Disord. 2005;84(2-3):251–257. Available from: https://dx.doi.org/10.1016/j.jad.2004.01.015.
Beck A, Steer R. and others, editor; 1987.
Wing J, Babor M, Brugha T, Burke J, Cooper J, Giel R, et al. SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Arch Gen Psychiatry. 1990;47:589–93. Available from: https://doi.org/10.1001/archpsyc.1990.01810180089012.
Cuellar AK, Johnson SL, Winters R. Distinctions between bipolar and unipolar depression. Clin Psychol Rev. 2005;25(3):307–339. Available from: https://dx.doi.org/10.1016/j.cpr.2004.12.002.
Mcguffin P, Farmer A, Harvey I. A polydiagnostic application of operational criteria in studies of psychotic illness. Develop- ment and reliability of the OPCRIT system. Arch Gen Psychia- try. 1991;48:764–70. Available from: https://doi.org/10.1001/archpsyc.1991.01810320088015.
Craddock M, Asherson P, Owen MJ, Williams J, Mcguffin P, Farmer AE. Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses. Br J Psychiatry. 1996;169:58–63. Available from: https://doi.org/10.1192/bjp.169.1.58.
Bowden CL. A different depression: clinical distinctions between bipolar and unipolar depression. J Affect Disord. 2005;84(2-3):117–125. Available from: https://dx.doi.org/10.1016/s0165-0327(03)00194-0.
Swann AC, Geller B, Post RM, Altshuler L, Chang KD, DelBello MP, et al. Practical Clues to Early Recognition of Bipolar Disorder. J Clin Psychiatry. 2005;07(01):15–21. Available from: https://dx.doi.org/10.4088/pcc.v07n0103.
Mitchell PB, Wilhelm K, Parker G, Austin MP, Rutgers P, Malhi GS. The clinical features of bipolar depression: a comparison with matched major depressive disorder patients. J Clin Psychiatry. 2001;62:212–228.
Forty L, Smith D, Jones L, Jones I, Caesar S, Cooper C, et al. Clinical differences between bipolar and unipolar depression. Br J Psychiatry. 2008;192(5):388–389. Available from: https://dx.doi.org/10.1192/bjp.bp.107.045294.
Grover S, Chakrabarti S, Avasthi A, Kate N, Bharadwaj V. Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy: A study from north India. Indian J Psychiatry. 2012;54:41–41. Available from: https://dx.doi.org/10.4103/0019-5545.94644.
Nisha A, Sathesh V, Punnoose V, Varghese P. A comparative study on psycho-socio-demographic and clinical profile of patients with bipolar versus unipolar depression. Indian J Psychiatry. 2015;57:392. Available from: https://dx.doi.org/10.4103/0019-5545.171842.
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