Abnormal Uterine Bleeding - A Clinicopathological Study Of 160 Cases

Abstract

Objective:To study the histopathology of endometrial biopsies in abnormal uterine bleeding and clinicopathological correlation. Methods:Endometrial biopsies obtained from 160 cases of abnormal uterine bleeding were studied followed by correlation of endometrial histopathology with parity, age and bleeding pattern. Results:Abnormal uterine bleeding was most frequent in multiparous women in 4thand 5th decades. The commonest bleeding pattern was menorrhagia. Endometrial abnormality was found in 53% cases which included endometrial hyperplasia (27%), mixed pattern endometrium (19%), endometritis (4%), endometrial polyp (2%) and endometrial carcinoma (1%). The frequency of endometrial hyperplasia was highest in multiparous women in 4th decade. The most common bleeding patterns in hyperplasia were menorrhagia (35%) and menometrorrhagia (30%). Forty one percent patients with menometrorrhagia had endometrial hyperplasia. Postmenopausal patients had predominantly proliferative, hyperplastic and mixed patterns of endometrium. Conclusion:Endometrial biopsy should be recommended during the work up of abnormal uterine bleeding to exclude organic pathology of endometrium.