Adding Clonidine to Ropivacaine in Brachial Plexus Block for Upper Limb Surgeries: Study of Hemodynamic Variables

Adding Clonidine to Ropivacaine in Brachial Plexus Block for Upper Limb Surgeries

  • Dr Virupakshamma Senior Resident, Department of Anesthesiology, Gadag Institute of Medical sciences, Gadag, Karnataka.
  • Ajay Basarigidad Senior Resident, Department of Anesthesiology, Gadag Institute of Medical sciences, Gadag, Karnataka.
Keywords: Clonidine, Ropivacaine, Hemodynamic Variables

Abstract

Background: Ropivacaine is a long acting amide local anaesthetic agent. It was first synthesized in 1957 along with bupivacaine and mepivacaine. It is a pure S-enantiomer while bupivacaine is a racemic mixture. Ropivacaine causes reversible inhibition of sodium ion influx, and thereby blocks impulse conduction in nerve fibres. This action is potentiated by dose-dependent inhibition of potassium channels. Subjects and Methods: This study was conducted on 60 patients undergoing upper limb surgeries aged between 18 to 55 years under supraclavicular block. Informed written consent was taken. Result values were recorded using a preset proforma. Results: There were 24 patients in Group R and 23 patients in Group RC belonging to ASA Grade I, and 6 patients in Group R and 7 patients in Group RC belonging to ASA Grade II which was considered statistically not significant. Conclusion: The combination produces improved analgesia, resulting in a prolonged effect and stable hemodynamics.

Published
2019-02-24
How to Cite
Virupakshamma, D., & Basarigidad, A. (2019). Adding Clonidine to Ropivacaine in Brachial Plexus Block for Upper Limb Surgeries: Study of Hemodynamic Variables. Academia Anesthesiologica International, 4(1), 15-18. https://doi.org/10.21276/aan.2019.4.1.4