@article{Virupakshamma_Basarigidad_2019, title={Adding Clonidine to Ropivacaine in Brachial Plexus Block for Upper Limb Surgeries: Study of Hemodynamic Variables}, volume={4}, url={https://aijournals.com/index.php/aan/article/view/468}, DOI={10.21276/aan.2019.4.1.4}, abstractNote={<p><strong>Background: </strong>Ropivacaine is a long acting amide local anaesthetic agent. It was first synthesized in 1957 along with bupivacaine and mepivacaine. It is a pure S-enantiomer while bupivacaine is a racemic mixture. Ropivacaine causes reversible inhibition of sodium ion influx, and thereby blocks impulse conduction in nerve fibres. This action is potentiated by dose-dependent inhibition of potassium channels. <strong>Subjects and Methods: </strong>This study was conducted on 60 patients undergoing upper limb surgeries aged between 18 to 55 years under supraclavicular block. Informed written consent was taken. Result values were recorded using a preset proforma. <strong>Results: </strong>There were 24 patients in Group R and 23 patients in Group RC belonging to ASA Grade I, and 6 patients in Group R and 7 patients in Group RC belonging to ASA Grade II which was considered statistically not significant. <strong>Conclusion: </strong>The combination produces improved analgesia, resulting in a prolonged effect and stable hemodynamics.</p&gt;}, number={1}, journal={Academia Anesthesiologica International}, author={Virupakshamma, Dr and Basarigidad, Ajay}, year={2019}, month={Feb.}, pages={15-18} }