Asymptomatic Isolated Cervical Tubercular Lymphadenopathy, How to Proceed?: A Case Series

Asymptomatic Isolated Cervical Tubercular Lymphadenopathy

  • Ravi Singh Dogra General Surgeon, Department of Surgery, Civil Hospital Ghumarwin, Bilaspur, Himachal Pradesh, India
  • Arjun Singh Anesthesiologist, Department of Anesthesia, Civil Hospital Sundarnagar, Mandi, Himachal Pradesh, India
  • Vinay Bhardwaj Physician, Department of Medicine, Civil Hospital Ghumarwin, Bilaspur, Himachal Pradesh, India
  • Poonam Junior Resident, Department of Anesthesia, Dr. R.P. Govt. Medical College, Tanda, Himachal Pradesh, India
  • Srijan Pandey Junior Resident, Department of Surgery, Dr. R.P. Govt. Medical College, Tanda, Himachal Pradesh, India
  • Gunjan Modgil Junior Resident, Department of Surgery, Dr. R.P. Govt. Medical College, Tanda, Himachal Pradesh, India
  • Arpit Goel Junior Resident, Department of Surgery, Dr. R.P. Govt. Medical College, Tanda, Himachal Pradesh, India
Keywords: Extra-pulmonary tuberculosis, Tubercular Cervical Lymphadenitis, FNAC, ZN stain, CBNAAT


Tuberculosis is a highly prevalent disease in developing countries, the majority of cases are pulmonary and rest are extra-pulmonary. Cervical LN tuberculosis is one of the most common types of extra-pulmonary tuberculosis. Isolated cervical tubercular Lymphadenitis without accompanying pulmonary tuberculosis or another form of tuberculosis in the body is rare and, when present, requires thorough clinical examination and investigation. In the investigation of such patients, FNAC plays a major role, and aspirate should be tested for AFB through ZN stain and CBNAAT (PCR). Cervical tubercular Lymphadenitis is mainly a disease of young with a female predominance. All patients of cervical tubercular Lymphadenitis must receive antitubercular therapy with strict follow up for compliance and possible side effects from treatment.


Download data is not yet available.


Chakraborty AK. Epidemiology of tuberculosis: current status in India. Indian J Med Res. 2004;120(4):248–276.

Tatar D, Senol G, Alptekin S, Gunes E. Assessment of Lymph node tuberculosis in two provinces in Turkey. Jpn J Infect Dis. 2011;64(4):316–321.

Golden MP, Vikram HR. Extra-pulmonary tuberculosis: an overview. Am Fam Physician. 2005;72(9):1761–1768.

Yesuf KM, Berhie KA, Yesuf JS, Atsedeweyn A, Abegaz ST. Analysis of Survival and Associated Risk Factors among HIV/AIDS Patients Who Started Antiretroviral Therapy (ART) in Central, Western and North Gondar Zones, North West Ethiopia. Asian J Med Res. 2018;7(3):7–12. Available from:

Kent DC. Tuberculosis lymphadenitis: not a localized disease process. Am J Med Sci. 1967;254:866–74.

Yew WW, Lee J. Pathogenesis of cervical tuberculous Lymphadenitis: pathways to anatomic localization. Tuber Lung Dis. 1995;76:275–281.

SelimoEsre- foa case report. The Journal of Laryngology & Otology. 1995;109(9):880–882. Available from: doi:10.1017/s0022215100131573.

Jha BC, Dass A, Nagarkar NM, Gupta R, Singhal S. Cervical tuberculous lymphadenopathy:changing clinical pattern and concepts in management. Postgrad Med J. 2001;77:185–192.

Geldmacher H, Taube C, Kroeger C, Magnussen H, Kirsten DK. Assessment of Lymph Node Tuberculosis in Northern Germany. Chest. 2002;121(4):1177–1182. Available from:

Penfold CN, Penfold CN. A review of 23 patients with tuberculosis of the head and neck. Br J Oral Maxillofacial Surg. 1996;34(6):508–510. Available from:

Polesky A, Grove W, Bhatia G. Peripheral tuberculous lym- phadenitis:epidemiology, diagnosis, treatment, and outcome. Medicine (Baltimore). 2005;84:350–62.

Konishi K, Yamane H, Iguchi H, Nakagawa T, Shibata S, Takayama M. Study of tuberculosis in the field of Otorhinolaryngology in the past 10 years. Acta Otolaryngol Suppl. 1998;598:244–253.

Dandapat MC, Mishra BM, Dash SP, Kar PK. Peripheral lymph node tuberculosis: A review of 80 cases. Br J Surg. 1990;77(8):911–912. Available from:

Shriner KA, Mathisen GE, Goetz MB. Comparison of Mycobacterial Lymphadenitis Among Persons Infected with Human Immunodeficiency Virus and Seronegative Controls. Clin Inf Dis. 1992;15(4):601–605. Available from:

Mittal P, Handa U, Mohan H, Gupta V. Comparative evaluation of fine needle aspiration cytology, culture, and PCR in diagnosis of tuberculous lymphadenitis. Diag Cytopathol. 2011;39(11):822–826. Available from:

Tadesse M, Abebe G, Abdissa K, Bekele A, Bezabih M, Apers L, et al. Concentration of Lymph Node Aspirate Improves the Sensitivity of Acid Fast Smear Microscopy for the Diagnosis of Tuberculous Lymphadenitis in Jimma, Southwest Ethiopia. PLoS One. 2014;9(9):e106726. Available from:

Baek CH, Kim SI, Ko YH, Chu KC. Polymerase chain reaction detection of Mycobacterium tuberculosis from fine- needle aspirate for the diagnosis of cervical tuberculous Lymphadenitis. Laryngoscope. 2000;110:30–34.

Estomba CMC, Reinoso FAB, Schmitz TR, Echeverri CCO, Cortés MJG, Hidalgo CS. Head and Neck Tuberculosis: 6-Year Retrospective Study. Acta Otorrinolaringol. 2016;67(1):9–14. Available from:

How to Cite
Dogra, R. S., Singh, A., Bhardwaj, V., Poonam, Pandey, S., Modgil, G., & Goel, A. (2020). Asymptomatic Isolated Cervical Tubercular Lymphadenopathy, How to Proceed?: A Case Series. Asian Journal of Medical Research, 9(2), 1-5.