Clinical Profile and Treatment Outcome of Patients with Cholecystolithiasis

Clinical Profile and Treatment Outcome of Patients with Cholecystolithiasis

  • Sarfaraz Alam Khan Lecturer, Department of General Surgery, People’s Dental College and Hospital, Kathmandu, Nepal https://orcid.org/0000-0001-8195-126X
  • Jiuneshwar Lal Jha Lecturer, Department of General Surgery, People’s Dental College and Hospital, Kathmandu, Nepal
  • Tika Ram Bhandari Associate Professor, Department of General Surgery, People’s Dental College and Hospital, Kathmandu, Nepal https://orcid.org/0000-0003-4424-5598
Keywords: Cholecystolithiasis, Clinical profile, treatment outcome

Abstract

Background: Cholecystolithiasis is a significant surgical problem. Variation in clinical symptoms of cholecystolithiasis forms the disease more thought-provoking. We aimed to explore demographics, the clinical profile of patients, and treatment outcomes of patients with cholecystolithiasis. Subjects and Methods: This is a retrospective study of patients with cholecystolithiasis from January 2018 to June 2021. The patient’s demographics, clinical profile, perioperative details, and treatment outcomes were analyzed. Results: A total of 304 patients (73 males) with cholecystolithiasis were included in the study. Median ages were 46 years (range: 19-71 years). Most of our patients 290 (95.6%) were symptomatic with the commonest symptom as upper abdominal pain. The conversion rate was 8.6%. Overall postoperative complications were found in 38 patients (12.2%). There was no mortality in this study. In logistic regression analysis, on multivariate analysis, out of the independent variables, sex (male), age (≥ 60 years), presence of comorbidity, and duration of surgery (≥ 2 hours), only the male gender was associated with an increased risk of postoperative complications (OR; 0.046, CI [0.018- 0.112], P < 0.05). Conclusion: Cholecystolithiasis is a common and significant surgical problem that usually presents with upper abdominal pain. Laparoscopic cholecystectomy is the standard care of treatment. Male gender is a risk factor for postoperative complications.

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Published
2022-06-24