Academia Journal of Surgery https://aijournals.com/index.php/ajs <p style="text-align: justify;"><strong>Academia Journal of Surgery (AJS)</strong> is an open-access; freely accessible, online and print Bi-Annual peer-reviewed international journal publishes a wide spectrum of advanced research in different fields of surgery and surgical sciences, covering etiology, diagnosis, therapy and prognosis aspects. <br><strong>Online ISSN: 2663-8347 | Print ISSN: 2663-8339</strong></p> Society for Healthcare and Research Development en-US Academia Journal of Surgery 2663-8339 Clinical Profile and Treatment Outcome of Patients with Cholecystolithiasis https://aijournals.com/index.php/ajs/article/view/2317 <p><strong>Background: </strong>Cholecystolithiasis is a significant surgical problem. Variation in clinical symptoms of cholecystolithiasis forms the disease more thought-provoking. We aimed to explore demographics, the clinical profile of patients, and treatment outcomes of patients with cholecystolithiasis. <strong>Subjects and Methods:</strong> This is a retrospective study of patients with cholecystolithiasis from January 2018 to June 2021. The patient’s demographics, clinical profile, perioperative details, and treatment outcomes were analyzed. <strong>Results: </strong>A total of 304 patients (73 males) with cholecystolithiasis were included in the study. Median ages were 46 years (range: 19-71 years). Most of our patients 290 (95.6%) were symptomatic with the commonest symptom as upper abdominal pain. The conversion rate was 8.6%. Overall postoperative complications were found in 38 patients (12.2%). There was no mortality in this study. In logistic regression analysis, on multivariate analysis, out of the independent variables, sex (male), age (≥ 60 years), presence of comorbidity, and duration of surgery (≥ 2 hours), only the male gender was associated with an increased risk of postoperative complications (OR; 0.046, CI [0.018- 0.112], P &lt; 0.05). <strong>Conclusion: </strong>Cholecystolithiasis is a common and significant surgical problem that usually presents with upper abdominal pain. Laparoscopic cholecystectomy is the standard care of treatment. Male gender is a risk factor for postoperative complications.</p> Sarfaraz Alam Khan Jiuneshwar Lal Jha Tika Ram Bhandari Copyright (c) 2022 Author https://creativecommons.org/licenses/by/4.0/ 2022-06-24 2022-06-24 5 1 1 4 Assessment of Wound Closure Methods in the Management of Open Injury: A Comparative Analysis https://aijournals.com/index.php/ajs/article/view/2372 <p><strong>Background: </strong>The current research was performed to establish the efficiency of vacuum assisted closure dressings in enhancing the healing procedure in chronic wounds, as compared to standard moist wound dressings. <strong>Subjects and Methods:</strong> Whole of 30 subjects were incorporated in the research. The included subjects were divided into two groups: Group 1 included subjects were treated with conventional dressings and in group 2 the included subjects were treated with VAC dressings. The subjects were informed about the study procedure and the written informed consent were obtained prior to the start of study. <strong>Results: </strong>Decrease in Wound Size. There was noteworthy diminish in wound size from day 0 to day 8 in VAC group in contrast to saline-wet-to-moist group. There was noteworthy reduce in the bacterial growth in the VAC group as compared to saline-wetto-moist group. <strong>Conclusion: </strong>VAC therapy is not the answer for all wounds; however, it can make a significant difference in many cases. VAC is a helpful instrument in poignant a wound to a point where more conventional dressings or more easy surgical reconstructive methods can be utilized. Present research concludes that negative pressure wound therapy is a helpful choice for management of wounds when compared to treatment with conservative dressing’s therapy in terms of contraction of wound, time occupied for wound healing and length of hospital stay.</p> Amit Ranchhodbhai Roza Shailesh K Rathod Copyright (c) 2022 Author https://creativecommons.org/licenses/by/4.0/ 2022-06-24 2022-06-24 5 1 5 7