A Rare Case: Gall Stone Induced Acute Pancreatitis with Normal Amylase and Lipase Levels

Gall Stone Induced Acute Pancreatitis with Normal Amylase and Lipase Levels

Keywords: Acute pancreatitis (AP), Gall stone, Amylase, Lipase


Acute pancreatitis (AP) is most commonly diagnosed by increased values of serum amylase and lipase. Acute pancreatitis where value of serum amylase and lipase is normal is very rare. This is a case of gall stone induced AP where levels of serum amylase and lipase are normal but the clinical suspicion and imaging are strongly confirming pancreatitis.


Download data is not yet available.


Vissers RJ, Abu-Laban RB, McHugh DF. Amylase and lipase in the emergency department evaluation of acute pancreatitis. J Emerg Med. 1999;17(6):1027–1037. Available from: https://dx.doi.org/10.1016/s0736-4679(99)00136-5.

Clavien PA, Robert J, Meyer P, Borst F, Hauser H, Her- rmann F, et al.. Acute Pancreatitis and Normoamylasemia; 1989. Available from: https://dx.doi.org/10.1097/00000658-198911000-00008.

Neki NS, Shergill GS, Singh A, Rampal VK, Nizami S, Singh T. Acute pancreatitis with normal amylase and lipase levels. Postgrad Med Inst. 2017;31(2).

Cartier T, Sogni P, Perruche F, Meyniard O, Claessens YE, Dhainaut JF, et al. Normal lipase serum level in acute pancreatitis: a case report. Emerg Med J. 2006;23(9):701–703. Available from: https://dx.doi.org/10.1136/emj.2006.037655.

Al-Bahrani AZ, Ammori BJ. Clinical laboratory assessment of acute pancreatitis. Clin Chim Acta. 2005;362(1-2):26–48. Available from: https://dx.doi.org/10.1016/j.cccn.2005.06.008.

Banks PA, Freeman ML. Practice Parameters Committee of the American College of Gastroenterology. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101(10):2379–400. Available from: https://doi.org/10.1111/j.1572-0241.2006.00856.x.

Whitcomb DC. Value of genetic testing in the management of pancreatitis. Gut. 2004;53(11):1710–1717. Available from:https://dx.doi.org/10.1136/gut.2003.015511.

Kylänpää-Bäck ML, Kemppainen E, Puolakkainen P, Hed- ström J, Haapiainen R, Perhoniemi V, et al.. Reliable screening for acute pancreatitis with rapid urine trypsinogen-2 test strip; 2000. Available from: https://dx.doi.org/10.1046/j.1365-2168.2000.01298.x.

Sternby B, O’Brien JF, Zinsmeister AR, DiMagno EP. What Is the Best Biochemical Test to Diagnose Acute Pancreatitis? A Prospective Clinical Study; 1996. Available from: https://dx.doi.org/10.4065/71.12.1138.

Frank B, Gottlieb K. Amylase Normal, Lipase Elevated: Is It Pancreatitis?; 1999. Available from: https://dx.doi.org/10.1111/j.1572-0241.1999.878_g.x.

Hiatt JR, Calabria RP, Passaro E, Wilson SE. The amy- lase profile: A discriminant in biliary and pancreatic dis- ease; 1987. Available from: https://dx.doi.org/10.1016/0002-9610(87)90261-3.

Shah AM, Eddi R, Kothari ST, Maksoud C, Digiacomo WS, Baddoura W. Acute pancreatitis with normal serum lipase: a case series. J Pancreas. 2010;11(4):369–72.