A Single Dose of Antibiotics in Laparoscopic Appendicectomy

A Single Dose of Antibiotics in Laparoscopic Appendicectomy

Keywords: Appendicectomy, Antibiotics, Outcome, Complications, Surgical Site Infection (SSI)

Abstract

Background: Single or multiple-dose regimens of antibiotics may rely on the patients medical situation and the patients susceptibility to infection. The present study was therefore planned to evaluate the effectiveness and outcomes of the single dose of antibiotics in patients undergoing laparoscopic appendicectomy. A simple, safe, and non-toxic drug is used for avoiding or eradicating contamination with a certain microorganism. Materials and Methods: The retrospective case study was conducted in Department of General Surgery, Bhaskar Medical College, Yenkapally, Moinabad, Ranga Reddy Dist., Telangana, India from March 2017 -February 2018 among 50 patients scheduled for laparoscopic appendicectomy. Laparoscopic appendicectomy patients were divided into two groups, one group of 30 patients received single dose pre-operative antibiotics and the other group of 20 patients received multiple doses of antibiotics. Results: Out of 50 patients, majority 84% were males and 16% were females. Out of 50 patients, 8 patients had SSI. Out of 50 patients, the majority 76% of the patients reported on day 2 and only 24% reported on day 1 of appendicectomy. 29 patients were discharged after a day stay in the hospital, 93% belonged to the single-dose group and 5% belonged to the multiple-dose group. The remaining 21 patients were discharged on day 2. The majority 95% belonging to the multiple-dose group were discharged on day 2 and 7% belonging to the single-dose group were discharged on day 2 as they have been kept under observation for infection. Conclusion: For basic, uncomplicated acute appendicitis, single dose of prophylactic antibiotics will help in cases of laparoscopic appendicectomy. There is no necessity for the post-operative administration of antibiotics.

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References

Danwang C, Bigna JJ, Tochie JN, Mbonda A, Mbanga CM, Nzalie RNT, et al. Global incidence of surgical site infection after appendectomy: a systematic review and meta-analysis. BMJ Open. 2020;10(2):e034266.

Danwang C, Mazou TN, Tochie JN, Nzalie RNT, Bigna JJ. Global prevalence and incidence of surgical site infections after appendectomy: a systematic review and meta-analysis protocol. BMJ Open. 2018;8(8):e020101.

Available from: https://dx.doi.org/10.1111/j.1742-4801.2004.00067.x.

Published
2020-06-24