Comparative Evaluation of Intrathecal Dexmedetomidine and Fentanyl with Hyperbaric Bupivacaine for Post-Operative Analgesia in Lower Abdominal Surgeries

Post Operative Analgesia In Lower Abdominal Surgeries

  • Arun Kumar Saxena Assistant Professors, Department of Anaesthesiology JNU Medical college Jaipur
  • Sapna Singh Assistant Professors, Department of Anaesthesiology JNU Medical college Jaipur
  • B.L. Mathur Professor and Head, Department of Anaesthesiology JNU Medical College Jaipur
  • Neena Rungta Professor, Department of Anaesthesiology JNU Medical College Jaipur
Keywords: Dexmedetomidine, Fentanyl and Bupivacaine

Abstract

Background: Spinal anaesthesia is the fastest and most reliable form of regional anaesthesia. Additions of intrathecaly adjuvants are useful for prolonging the spinal anaesthesia effects.Subjects and Methods:The Patients were divided in three groups; Group C (control group) = received   15 mg (3 ml) of hyperbaric bupivacaine intrathecaly.  Group D = received 15 mg (3 ml) of hyperbaric bupivacaine plus 4μgDexmedetomidine intrathecally. Group F = received Hyperbaric Bupivacaine 15mg (3ml) plus 25μg fentanylintrathecally.Results: For the total duration of sensory block p- value is 0.000003, which is less than 0.05 (α) and is highly significant. From the above p – value and scheffe post hoc test we conclude that the Bupivacaine + Dexmedetomidine has prolonged duration of sensory block as compared to bupivacaine alone and in combination with fentanyl. For the motor block p- value is 0.000000 and is less than 0.05 (α). It is highly significant. For the demand of Analgesic p-value is 0.0000001 and is less than 0.05 (α) i.e. there is highly significant difference between them. Conclusion: Intrathecal Dexmedetomidine  used as an adjuvant to bupivacaine in spinal block seems to be a good alternative to intrathecal fentanyl as it produces  early  onset  and prolonged  duration  of  sensory and motor block  without  significant haemodynamic alteration and side effects.

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Published
2019-10-01
How to Cite
Arun Kumar Saxena, Sapna Singh, B.L. Mathur, & Neena Rungta. (2019). Comparative Evaluation of Intrathecal Dexmedetomidine and Fentanyl with Hyperbaric Bupivacaine for Post-Operative Analgesia in Lower Abdominal Surgeries. Academia Anesthesiologica International, 4(2), 193-196. https://doi.org/10.21276/aan.2019.4.2.44