Effects of Intubation on heart rate: Xylocard and Esmolol

Effects of Intubation on heart rate

Abstract

Background: Lignocaine is a local anaesthetic of moderate potency and duration with good penetrative power and rapid onset of action carbonated lignocaine has remarkable penetrative power, rapid onset of action a high incidence of motor block and a reduced incidence of missed segments (When used for epidural anaesthesia) when compared to hydrochloride of lignocaine. Subjects and Methods: Seventy five (75) patients belonging to ASA grade 1 & 2 scheduled for general surgical, orthopaedic surgical, ENT, gynaecological surgical producers were studied. Results: The age of the patients varied from 10 to 60 years. In our study, the heart rate in controls (Group A) before induction was 86+/-10 rose to 93+/-12 and 107+/-13 after induction and after laryngoscopy + ETI respectively. The changes seen after endotracheal intubation alone was statistically very highly significant (<0.001).           In Group B, the pre induction heart rate was 94+/-17, which increased to 99+/-13, after induction.This increase not significant (P>0.05). There was an increases of 15 at laryngoscopy + ETI which was very highly significant (P<0.001). Conclusion: In Group C, the pre induction heart rate of 96+/-15 increased to 97+/-11 at induction and to 108+/-15 following endotracheal intubation.