Assessment of Effect of Midazolam on Anxiety in Children Undergoing Surgical Procedures

Assessment of Effect of Midazolam on Anxiety in Children

Abstract

Background: To assess effect of midazolam on anxiety in children undergoing surgical procedures. Methods: Fifty- four children age ranged 6-14 years scheduled for surgery were divided into group 1 containing those who were undergoing surgery for the first time and group 2 had patients with a history of previous surgery within the last 2 years. Baseline anxiety of children was measured using the modified Yale Preoperative Anxiety Scale (mYPAS). Results: Time from premedication to second assessment (min) was 23.4 in group 1 and 23.7 in group 2, time from premedication to parental separation (min) was 28.4 in group 1 and 28.3 in group 2, time from premedication to mask induction (min) was 30.5 in group 1 and 31.7 in group 2, anxiety score at baseline was 33.4 in group 1 and 42.5 in group 2, after 20 minutes was 31.6 in group 1 and 34.8 in group 2. Incidence of high anxiety (mYPAS >30) at baseline was 20             in group 1 and 26 in group 2, after 20 minutes was 19 in group 1 and 20 in group 2. A non- significant difference was observed (P> 0.05).  Conclusion: No difference was seen in anxiety scores after premedication with midazolam as in children with history of previous anaesthesia exposure and those experiencing anaesthesia for the first time.