Comparative Evaluation of Analgesic Efficacy of Intra-Articular Vs Intrathecal Clonidine in Arthroscopic Anterior Cruciate Ligament Repair: A Randomised, Double Blind Prospective Study

Arthroscopic Anterior Cruciate Ligament Repair

  • Shilpa Sarathy Department of Anaesthesia, Pursuing DNB Critical Care at Fortis Hospital, Mumbai, Maharashtra, India https://orcid.org/0000-0001-8471-8754
  • Vrinda Oza Assistant Professor, Department of Anaesthesia, P.D.U Medical College, Rajkot, Gujarat, India
  • Vandana Parmar Professor and Head, Department of Anaesthesia, P.D.U Medical College, Rajkot, Gujarat, India
  • Payal Adhiya Senior Resident, Department of Anaesthesia, P.D.U Medical College, Rajkot, Gujarat, India
  • Krupa Patel Senior Resident, Department of Anaesthesia, P.D.U Medical College, Rajkot, Gujarat, India
Keywords: Clonidine, anterior cruciate ligament repair, arthroscopy, post operative analgesia

Abstract

Background: The purpose of this study was to compare the analgesic effects of Clonidine as an adjuvant through different routes for ACL repair surgeries. Subjects and Methods: Ninety adult patients of ASA grade I and II, both sex, age 18-60 years scheduled for ACL repair under Sub-arachnoid block (SAB) were randomly allocated into three groups. All patients received 0.5% bupivacaine intrathecally as in control group. Group IT received 1 µg/kg of clonidine in saline intrathecally with hyperbaric bupivacaine. Group IA received Clonidine 1µg/kg with 30 ml saline injected intra-articularly at the end of surgery. The duration of analgesia and block characteristics were the primary outcomes studied. Results : Statistical analysis was done by Statistical Package for Social Sciences (SPSS version 20.0) and epi info 7 (CDC Atlanta). The mean duration of Analgesia in Group IA(5.9  1.02h) was significantly (p=0.01) longer than that of Group IT(5.2  0.85h) and Group C (4.0  0.78h) and the requirement of total number of rescue analgesics in 24 hr period was lesser in Group IA(1.1  0.33) and Group IT (1.3  0.50) than  Group C (3.4 0.69). The mean duration of sensory and motor block in Group IT was (4.5 0.88 h) and (3.8 0.78 h) respectively which was significantly longer than other groups. Conclusion: Clonidine is a useful adjuvant in prolonging analgesia through various routes for ACL repair surgeries arthroscopically. Intra-articularly administered clonidine provided most effective postoperative analgesia with least hemodynamic changes and complications.

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Published
2021-06-20
How to Cite
Sarathy, S., Oza, V., Parmar, V., Adhiya, P., & Patel, K. (2021). Comparative Evaluation of Analgesic Efficacy of Intra-Articular Vs Intrathecal Clonidine in Arthroscopic Anterior Cruciate Ligament Repair: A Randomised, Double Blind Prospective Study. Academia Anesthesiologica International, 6(1), 131-136. Retrieved from https://aijournals.com/index.php/aan/article/view/1988
Section
ORIGINAL ARTICLE