Evaluation of the Efficacy and Safety of Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI

Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI

  • Khushboo Bhavsar Ex- Resident, Department of Anaesthesia, C.U.Shah Medical College and Hospital, Surendranagar, Gujarat, India
  • Naynaben Vaghani Assistant Professor, Department of Anaesthesia, C.U.Shah Medical College and Hospital, Surendranagar, Gujarat, India
  • Annirudh Gadhavi Assistant Professor, Department of Anaesthesia, C.U.Shah Medical College and Hospital, Surendranagar, Gujarat, India
  • Rajesh Naval Professor, Department of Anaesthesia, C.U.Shah Medical College and Hospital, Surendranagar, Gujarat, India
Keywords: Dexmedetomidine, Propofol, Recovery time, Sedation

Abstract

Background: The present research was performed to assess the efficacy and safety of dexmedetomidine versus propofol for sedation in children endures MRI. Subjects and Method: This prospective randomized research was performed in the Department of Anaesthesia at Medical College, Surendranagar. Baseline HR, systolic blood pressure (SBP), respiratory rate (RR), and oxygen saturation (SpO2) Onset of sedation were documentated on entrance to the research room. Children were divided in dexmedetomidine (Group D) or propofol (Group P). Group D (n= 30) received injection dexmedetomidine1µg/kg for 10 min trailed by constant Dexmedetomidine 0.5-0.7µg/kg/h. Group P (n = 30) received injection propofol 1 mg/kg bolus trailed by constant infusion of 100 µg/kg/min. Site and duration of MRI, onset of sedation (RSS = 5), duration of sedation, incremental infusion requirement, and recovery time were recorded. Results: Mean age, weight, and sex ratio among the two groups were comparable. The mean time to attain the requisite level of sedation was comparable in both the groups The utilization of Dexmedetomidine for postoperative analgesia consequences in considerably fewer added pain medication and sluggish heart rates than a control group. Conclusion: Dexmedetomidine is analogous with propofol as maintenance anesthetic agent and it can create improved organize of hemodynamic erratics. Propofol has a benefit of given that quick onset of sedation and faster revival instance.

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Published
2021-06-05
How to Cite
Khushboo Bhavsar, Naynaben Vaghani, Annirudh Gadhavi, & Naval, R. (2021). Evaluation of the Efficacy and Safety of Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI. Academia Anesthesiologica International, 6(1), 101-105. Retrieved from https://aijournals.com/index.php/aan/article/view/1955
Section
ORIGINAL ARTICLE