Evaluation of the Eﬃcacy and Safety of Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI
Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI
Background: The present research was performed to assess the efficacy and safety of dexmedetomidine versus propofol for sedation in children endures MRI. Subjects and Method: This prospective randomized research was performed in the Department of Anaesthesia at Medical College, Surendranagar. Baseline HR, systolic blood pressure (SBP), respiratory rate (RR), and oxygen saturation (SpO2) Onset of sedation were documentated on entrance to the research room. Children were divided in dexmedetomidine (Group D) or propofol (Group P). Group D (n= 30) received injection dexmedetomidine1µg/kg for 10 min trailed by constant Dexmedetomidine 0.5-0.7µg/kg/h. Group P (n = 30) received injection propofol 1 mg/kg bolus trailed by constant infusion of 100 µg/kg/min. Site and duration of MRI, onset of sedation (RSS = 5), duration of sedation, incremental infusion requirement, and recovery time were recorded. Results: Mean age, weight, and sex ratio among the two groups were comparable. The mean time to attain the requisite level of sedation was comparable in both the groups The utilization of Dexmedetomidine for postoperative analgesia consequences in considerably fewer added pain medication and sluggish heart rates than a control group. Conclusion: Dexmedetomidine is analogous with propofol as maintenance anesthetic agent and it can create improved organize of hemodynamic erratics. Propofol has a benefit of given that quick onset of sedation and faster revival instance.
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