A Study on Effects of Dexmedetomidine Used as an Adjuvant in Epidural Post-Operative Analgesia

Effects of Dexmedetomidine Used as an Adjuvant

Abstract

Background: Epidural anaesthesia with adjuvant is normally used for postoperative pain management in infra umbilical surgeries but search for ideal adjuvant without any side effect goes on. Aim: This study was done to assess the onset and duration of sensory and motor block and side effects of dexmedetomidine, when used as an adjuvant in epidural anaesthesia in infra umbilical surgeries. Subjects and Methods: 60 patients of ASA status I and II, posted for infra umbilical surgeries were randomly allocated into two groups of 30 each. Group L patients received epidural 0.5% levobupivacaine. Group LD patients received epidural 0.5% levobupivacaine and 1?g/kg dexmedetomidine. Preoperative and postoperative block characteristics as well as hemodynamic parameters and side effects were monitored. Results: Dexmedetomidine as an adjuvant had an earlier onset and longer duration of sensory and motor block compared to levobupivacaine alone. Sedation scores were statistically significant with dexmedetomidine group in comparison to levobupivacaine alone group. Conclusion:  Dexmedetomidine, as an adjuvant to epidural levobupivacaine provided prolonged analgesia in infraumbilical surgeries.