Assessment of Pulmonary Function Test in Patients with Diabetes Mellitus

Pulmonary Function Test in Patients with Diabetes Mellitus

Abstract

Background: The aim is to assess pulmonary function test in patients with diabetes mellitus. Subjects and Methods: One hundred fifteen type II diabetes mellitus of both genders were classified into group I. Equal number of healthy controls were put in group II. We recorded forced vital capacity (FVC) (litres), forced expiratory volume in 1 second (FEV₁), FEV1/FVC (%), forced expiratory flow during 25% of FVC (FEF₂₅), forced expiratory flow during 50% of FVC (FEF₅₀), forced expiratory flow during 75% of FVC (FEF₇₅), forced expiratory flow during 2575% of FVC (FEF₂₅₇₅), forced expiratory flow during 0.21.2 litres of FVC (FEF_0.21.2), and peak expiratory flow rate (PEFR). Results: Group I were type II diabetes and group II were control. Each group had 75 males and 40 females. The mean age of patients in group I was 57.2 years and in group II was 56.2 years. The mean weight was 62.4 kgs in group I and 60.2 kgs in group II. The mean height was 156.7 cm in group I and 153.7 cm in group II. There was non- significant difference in age, weight and height distribution between both group with p value >0.05. The mean FVC in group I was 76.4 litres and in group II was 92.1 litres, FEV1 was 77.3 in group I and 86.5 in group II, FEV1/ FVC was 1102.4 in group I and 108.8 in group II, PEFR was 56.2 and 75.4, FEF₂₅ was 60.8 and 81.9, FEF₅₀ was 61.2, FEF₇₅ was 73.4 in group I and 84.7, FEF_25-75 was 64.7 in group I and 73.2 in group II, FEF_0.2-1.2 was 70.1 in group I and 91.4 in group II. The difference between parameters in both groups was significant (P< 0.05).  Conclusion: Pulmonary function tests were greatly reduced in type II diabetics as compared to healthy subjects.