Iron and Oxidative Stress in Pregnancy in Anemic Indian Women

Abstract

Objectives: Iron deficiency anemia is known to be associated with oxidative stress. Pregnancy itself, due to its mitochondria rich placenta generating reactive oxygen species, is more prone to oxidative stress. The aim of this study was to evaluate the role of oxidative stress in anemia in pregnancy and its correlation to the serum iron levels. Methods: This case control study evaluated 33 pregnant women with anemia (Hb=11gms/dl) and 20 normal pregnant women without anemia admitted at VaniVilas Hospital, Bangalore. Their serum samples were analysed for Iron, MDA and AOPP levels and were compared for any significant differences between the two groups. Results: Serum iron, MDA and AOPP were significantly different in pregnancy with anemia as compared to pregnancy without anemia. Conclusion: The study demonstrates that pregnancy with anemia with low iron levels is associated with increased oxidative stress.