An Unusual Case of Pulmonary Alveolar Microlithiasis Masquerading as Pulmonary Tuberculosis

An Unusual Case of Pulmonary Alveolar Microlithiasis Masquerading as Pulmonary Tuberculosis

  • Nadia Ilyas Junior Resident (Pathology), Department of Pathology, Government Medical College and Hospital, Nagpur
  • Sandhya Poflee Associate Professor, Department of Pathology, Government Medical College and Hospital, Nagpur
  • Vedita Bobde Assistant Professor, Department of Pathology, Government Medical College and Hospital, Nagpur
  • Satish Helwatkar Assistant Professor, Department of Pathology, Government Medical College and Hospital, Nagpur
Keywords: Pulmonary Alveolar Microlithiasis, Imaging findings in PAM, Histopathological features of PAM

Abstract

Pulmonary Alveolar Microlithiasis (PAM) is a rare chronic lung disease characterized by bilateral intra-alveolar calcium and phosphate deposition throughout the lung parenchyma. PAM is known to occur over wide age range. Exact etiopathogenesis of PAM is not known and long term survival is uncertain. Patient can be asymptomatic or present with progressive pulmonary symptoms. Radiological features of PAM are pathognomic for radiologist who is aware of this rare pulmonary disease. However the changes of PAM on imaging can be misdiagnosed as those due to pulmonary tuberculosis which is a relatively common diagnosis in the Indian setting. Definitive diagnosis is based on typical microscopic features seen on transbronchial or open lung biopsy.We report a case of 41 years old female who was treated as a case of pulmonary tuberculosis for two years without relief of symptoms at a peripheral medical centre. Final diagnosis of PAM was made on the basis of characteristic radiological findings and microscopic features at our Institute.

Published
2019-12-30
How to Cite
Nadia Ilyas, Sandhya Poflee, Vedita Bobde, & Satish Helwatkar. (2019). An Unusual Case of Pulmonary Alveolar Microlithiasis Masquerading as Pulmonary Tuberculosis. Asian Journal of Medical Research, 8(4), PT01-PT03. https://doi.org/10.21276/ajmr.2019.8.4.PT1