Assessment of the Different Modalities of Treatment in Paediatric Cerebral Palsy Patients

Different Modalities of Treatment in Paediatric Cerebral Palsy Patients

  • Gaurang Dilip Kumar Pabani Assistant Professor, Department of Pediatrics, GMERS Medical College and Civil Hospital, Sola, Ahmedabad, India
  • Rajeshri Rajendra Mehta Assistant Professor, Department of Pediatrics, Dr. M K Shah Medical College and Research Centre, Chandkheda, Ahmedabad, India
  • Pramod Chandulal Shah Associate Professor, Department of Pediatrics, Dr. M K Shah Medical College and Research Centre, Chandkheda, Ahmedabad, India
Keywords: Cerebral Palsy, Citicoline, Physiotherapy, Paediatric


Background: To assess the effects of injection of citicoline in combination with physiotherapy versus physiotherapy alone, to advance the functional outcome in paediatric patients with cerebral palsy. Subjects & Methods: A total of 150 paediatric patients diagnosed with cerebral palsy were incorporated into the study. The average age of the patient included in the study was found to be 36 months. All the patients enrolled in the study were referred to the paediatric neurological department. Results: The mean age of the patient was 36 10 months. Out of the 150 total patients, 60% were boys and 40% were girls. When the percentage of improvement was compared between the groups, the study group was established to be statistically significant. (P = 0.02). Conclusion: Citicoline is efficient and secure in the treatment of gross motor function combination with physiotherapy in patients with cerebral palsy. Physical therapy is frequently the first move in managing cerebral palsy.


Download data is not yet available.


Geschwind N. The apraxias: Neural mechanisms of disorders of learned movement: The anatomical organization of the language areas and motor systems of the human brain clarifies apraxic disorders and throws new light on cerebral dominance. Am Sci. 1975;63(2):188–95.

Bax M, Goldstein M, Rosenbaum P, Leviton A, Paneth N, Dan B, et al.. Proposed definition and classification of cerebral palsy, April 2005; 2005. Available from:

Rosenbaum P, Paneth N, Leviton A, Goldstein M, Bax M, Damiano D. A Report: The Definition and Classification of Cerebral Palsy. Dev Med Child Neurol Suppl. 2006;109:8–14.

Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, et al. Practice Parameter: Diagnostic assessment of the child with cerebral palsy: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology. 2004;62(6):851–863. Available from:

Jan MMS. Cerebral Palsy: Comprehensive Review and Update. Ann Saudi Med. 2006;26(2):123–132. Available from:

Ingram TTS. The Neurology of Cerebral Palsy. Arch Dis Child. 1966;41(218):337–357. Available from:

Stavsky M, Mor O, Mastrolia SA, Greenbaum S, Than NG, Erez O. Cerebral Palsy—Trends in Epidemiology and Recent Development in Prenatal Mechanisms of Disease, Treatment, and Prevention. Front Pediatr. 2017;5:21. Available from:

Miller D, Grossman R, Reingold S, Mcfarland H. The role of magnetic resonance techniques in understanding and managing multiple sclerosis. Brain. 1998;121(1):3–24. Available from:

Sharan D. Orthopedic surgery in cerebral palsy: Instructional course lecture. Indian J Orthop. 2017;51(3):240–255. Available from:

Nasiri J, Kargar M. Combination of citicoline and phys- iotherapy in children with cerebral palsy. Int J Prev Med. 2014;5(10):1308–1313.

Galea MP. Physical modalities in the treatment of neurological dysfunction. Clin Neurol Neurosurg. 2012;114(5):483–488. Available from:

Patel DS, Sharma N, Patel MC, Patel BN, Shrivastav PS, Sanyal M. Liquid Chromatography Tandem Mass Spectrometry Method For Determination Of Febuxostat In Human Plasma To Support A Bioequivalence Study. J Adv Pharm Technol. 2013;1(1):37–50. Available from:

Hirschberger RG, Kuban KCK, O’Shea TM, Joseph RM, Heeren T, Douglass L, et al. Co-occurrence and severity of neurodevelopmental burden (cognitive impairment, cerebral palsy, autism spectrum disorder, and epilepsy) at age 10 years in children born extremely preterm. Pediatr Neurol. 2018;79:45–52. Available from:

Das SP, Ganesh GS. Evidence-based Approach to Physical Therapy in Cerebral Palsy. Indian J Orthop. 2019;53(1):20–34. Available from:

Shamsoddini A, Amirsalari S, Hollisaz MT, Rahimnia A, Khatibi-Aghda A. Management of Spasticity in Children with Cerebral Palsy. Iran J Pediatr. 2014;24(4):345–351.

Russman BS, Ashwal S. Evaluation of the child with cerebral palsy. Semin Pediatr Neurol . 2004;11(1):47–57. Available from:

Weiss GB. Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline. Life Sci. 1995;56(9):637–60. Available from:

Segura T, Calleja S, Jordan J. Recommendations and treatment strategies for the management of acute ischemic stroke. Expert Opin Pharmacother. 2008;9(7):1071–1085. Available from:

Pawar P, Ramakrishnan S, Mumbare S, Patil M. Effectiveness of the addition of citicoline to patching in the treatment of amblyopia around visual maturity: A randomized controlled trial. Indian J Ophthalmol. 2014;62(2):124–129. Available from:

How to Cite
Gaurang Dilip Kumar Pabani, Mehta, R. R., & Shah, P. C. (2020). Assessment of the Different Modalities of Treatment in Paediatric Cerebral Palsy Patients. Asian Journal of Clinical Pediatrics and Neonatology, 8(4), 9-12.
Original Article