Asian Journal of Clinical Pediatrics and Neonatology <p><strong class="pull-left">Asian Journal of Clinical Pediatrics and Neonatology (AJCPN)</strong>&nbsp;&nbsp;is an open-access; freely accessible, online and print Quarterly peer-reviewed international journal publishes a wide spectrum of advanced research in different fields of pediatrics and neonatology, covering etiology, diagnosis, therapy and prognosis aspects. <br><strong>Online ISSN: 2347-3363 | Print ISSN: 2347-3355</strong></p> en-US (Dr. Rohit Varshney) (Mr Shadan Pasha) Mon, 28 Dec 2020 09:28:23 +0000 OJS 60 A Prospective Randomized Study on Dietary Predictor of Anaemia Among Children Aged 6 Months to 3 Years <p><strong>Background: </strong>The present study aimed to record anemia and predictor of anemia in 6 months to 3 years children. <strong>Subjects and Methods: </strong>The present study was conducted on 280 children age ranged 6 months -3 years of both genders. Children with Hb level &lt;11 g/dL were considered anemic, and graded as mild (10–10.9 g/dL), moderate (7–9.9 g/dL), and severe (&lt;7 g/dL). <strong>Results: </strong>There were 150 male and 130 female children and anemia was seen in 56 male and 70 female children. Anemia was detected in 25 children age ranged 6-12 months, 45 in age group 1-2 years and 56 in 2-3 years. 85 anemic children were &lt;2.5 kgs at birth whereas 41 were &gt;2.5 kgs at birth. 68 were not breastfed while 58 were on exclusive breastfeed. <strong>Conclusion: </strong>Authors found that low birth weight, female gender, not on breastfeed, vegetables and meat non consumers are determinants of anaemia in children.</p> Srikrishna Surampudi, K. Muralidhar Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Clinical and Demographic Profile of Diarrheal Patients of Pediatric Age: A Cross-Sectional Study <p><strong>Background : </strong>Sometimes, diarrhea may co-exist with vomiting, fever, abdominal pain, etc. depending upon its etiology. Diarrheal diseases can also lead to significant malnutrition and dehydration. Thus, at the tertiary care center, a study was conducted with an aim to center on the clinical and sociodemographic profile of infants and children presenting with acute diarrhea. <strong>Subjects and Methods: </strong>It was a prospective, observational clinical study that began after obtaining approval from the Institutional Ethics Committee. It was conducted at the Department&nbsp;&nbsp; of Pediatrics, Gujarat Adani Institute of Medical Science, Bhuj, Kutch for a period of 2 years. The sample size was 200 with 2 groups A and&nbsp;&nbsp;&nbsp; B having 100 patients each. Accordingly, their clinical and demographic profile was also noted and studied in 2 groups. Various parameters analyzed were age and gender distribution, chief complaints, feeding practices, nutritional status and assessment of dehydration. <strong>Results: </strong>Mean age S.D were (2.25 1.40) and (2.49 1.39) years in group A and B respectively. Exclusive breastfeeding (EBF) for 6 months was given in a&nbsp; large no. of group A and B patients i.e. 52 (52%) and 58(58%) respectively. Few others were given for 4, 5, or 7 months. Maximum patients 58 (58%) of A and 52 (50%) of B group had no dehydration whereas remaining 42 (42%) and 48 (48%) patients had some dehydration respectively. <strong>Conclusion: </strong>Fever and vomiting were the complaints mainly regularly linked with diarrhea. a bit fewer than half of the children under research had some-dehydration. Greater parts of the patients were completely breastfed for six months.</p> Ekta Acharya Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Assessment of the Different Modalities of Treatment in Paediatric Cerebral Palsy Patients <p><strong>Background: </strong>To assess the effects of injection of citicoline in combination with physiotherapy versus physiotherapy alone, to advance the functional outcome in paediatric patients with cerebral palsy. <strong>Subjects &amp; Methods: </strong>A total of 150 paediatric patients diagnosed with cerebral palsy were incorporated into the study. The average age of the patient included in the study was found to be 36 months. All the patients enrolled in the study were referred to the paediatric neurological department. <strong>Results: </strong>The mean age of the patient was 36 10 months. Out of the 150 total patients, 60% were boys and 40% were girls. When the percentage of improvement was compared between the groups, the study group was established to be statistically significant. (P = 0.02). <strong>Conclusion: </strong>Citicoline is efficient and secure in the treatment of gross motor function combination with physiotherapy in patients with cerebral palsy. Physical therapy is frequently the first move in managing cerebral palsy.</p> Gaurang Dilip Kumar Pabani, Rajeshri Rajendra Mehta, Pramod Chandulal Shah Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Outcome of Patients Admitted To PICU and NICU In Relation To PRISM III Score in a Tertiary Care Hospital <p><strong>Introduction: </strong>Pediatric intensive care units (PICU) are an indispensable component of a successful health care establishment. They play a crucial part in reducing morbidity and mortality in the adolescent group. Several models and scores have been tried for internal auditing and in detecting the case fatality rate of a patient admitted in PICU and NICU. This helps the clinician in triaging patient care as and when required. The PRISM III score is widely used in PICU and NICU for the same. To evaluate the validity of the PRISM III score in predicting mortality in children admitted to PICU and NICU in a tertiary care hospital and to predict the probability of death of various PRISM III scores. <strong>Subjects and Methods: </strong>260 patients admitted to PICU and NICU were included in the study after obtaining informed consent from parents/guardians. Each patient was evaluated for the parameters in the PRISM III score and blood was drawn to send for investigations and results were entered in the proforma and were evaluated. <strong>Results: </strong>There was an increase in mortality rate with raise in PRISM III score. PRISM III offered a fair predictive power with the area under the curve 0.7 with 95% C.I. Out of 260 patients included in the study 24(9.2%) were dead. Variables like systolic BP, abnormal mental status, pupillary reflex, acidosis, and low platelet counts were significantly associated with a higher mortality rate. <strong>Conclusion: </strong>Evaluation of mortality and outcome of a patient admitted in PICU in a tertiary care hospital is best predicted by PRISM III score.</p> Khaleelullah MD Shakil, Pavan D. Kumar, Sreenivasa B., Talatam Sivachand Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Correlation Study of AIOS (Acute Illness Observation Scale) Score with Radiological Findings and Pulse Oximetry in Community-Acquired Pneumonia (Cap) Among Children Aged 2 To 59 Months <p><strong>Background: </strong>Community-acquired pneumonia (CAP) is one of the primary causes of mortality in infants and young children. Acute Illness Observation Score (AIOS) - act as the best and accurate indicator for the same. Hence in this study, AIOS was used to relate X-ray abnormalities and pulse oximeter finding for early assessment in children with ARI. <strong>Subjects and Methods: </strong>This was a descriptive epidemiological study conducted for a period of 24 months. Children aged from 2 months to 59 months who had symptoms and signs suggestive of pneumonia were involved in the study. Pulse oximetry reading on admission was noted. AIOS scoring is done on each subject. Chest X-ray was taken and interpreted. <strong>Results: </strong>The majority of patients fall in the age group of 2- 12 months (57.2%). CXR showed abnormal radiological changes in 54.0%, among them endpoint consolidation, was seen in 40.20% and infiltrates seen in 59.7%. 67 patients had spo2 &gt; 92% at admission, among them 44 (65.67 %) had normal &amp; 23 (34.32 %) had abnormal chest X-ray. 57.3 % (43/75) children with AIOS of 10 had normal x-ray &amp; 42.66% (32/75) had abnormal x-ray. AIOS with Spo2 reading showed a good correlation (p&lt;0.05) indicating that high AIOS scores are associated with low SpO2 scores. <strong>Conclusion: </strong>This study shows that with the help of AIOS scoring, fair association with an initial pulse oximeter reading and X-ray abnormalities can be done which can be utilized as an early combining tool for risk assessment and management.</p> Pavan D. Kumar, Khaleelullah MD Shakil, Sreenivasa B., Talatam Sivachand Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Iron Deficiency Anemia as a Risk Factor for First Febrile Seizures a Case Control Study <p><strong>Background: </strong>Febrile seizures in children are a common problem. Iron deficiency anaemia is known, among other contributing factors, to be an aggravating factor in febrile seizures. Iron deficiency anaemia is a condition that can be avoided and managed. The study goal was to identify iron deficiency anaemia as a trigger factor for febrile seizures (FS). To determine the association between Iron Deficiency Anemia (IDA) and the first episode of febrile seizures (FFS). <strong>Subjects and Methods: </strong>Investigation like hemoglobin, blood indices (MCV, MCH), and serum iron and serum ferritin are done for detection of iron deficiency anaemia and their relationship with the first episode of febrile seizure was observed. <strong>Results: </strong>In our study comprising 50 cases and 50 controls, 58% (29) of cases were diagnosed as IDA with FS, 18% (9) of controls were diagnosed as IDA with Febrile Illness (FI). This suggests IDA as a risk factor for febrile seizures with a significant P value of &lt;0.001. Among 50 cases 42% (21) cases have FS without IDA and among 50 controls 82% (41) controls have FI without IDA were present in the current study. <strong>Conclusion: </strong>IDA was more common in children with FS than in those with febrile illness (FI) disease alone. The result suggests that the IDA can be a contributing factor to the FFS. Screening of IDA of children with FFS should be regarded. Fever can worsen the negative effects of anaemia or iron deficiency on the brain, which can lead to seizures.</p> V. Ramgopal Rao, P. Anil Kumar Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 Study of Clinical Profile of Neonatal Seizures in Level III NICU <p><strong>Background: </strong>During the neonatal age, seizures are the most distinctive sign of neurological disease. Convulsive symptoms are the most promi- nent forms of neonatal neurological disorders. The goal of this research was to have a better view of the epidemiology, etiology, incidence, forms and mortality of neonatal seizures in our hospital. This research was undertaken to evaluate the prevalence, forms of neonatal seizures, etiology, occurrence period and correlation with etiology, and to establish the mortality correlated with neonatal seizures. For research the etiology and its etiological connection, the occurrence of neonatal seizures. <strong>Subjects and Methods: </strong>A comprehensive history was collected for the antenatal, natal, postnatal and family history. Age of initiation, form, duration and amount of seizures, consciousness before and after the seizures were taken. Comprehensive neonate examination was performed after detailed history. Relevant investigations were carried out depending upon clinical presentation. <strong>Results: </strong>In our analysis of 200 neonatal seizures, 194 had one of the four classically identified neonatal seizures. Multifocal clonic seizures were among the most common type of seizures 36% (72 cases) followed by subtle 27% (54 cases), GTS 26% (52 cases), Myoclonic 7% (15 cases), mixed type of seizures 3% (6 cases) and focal clonic seizures 1% (2 cases). <strong>Conclusion: </strong>Because neonatal seizures are most frequently due to birth asphyxia, better antenatal and perinatal care reduces birth asphyxia and if mothers are identified as high-risk. The impact of neonatal seizures is thereby minimized. Subtle seizures are the most frequent form of psychiatric seizure; thus, close monitoring of newborns at risk is important.</p> P. Anil Kumar, V. Ramgopal Rao Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000 A Cross-Sectional Study to Determine the Prevalence of Gastroesophageal Reflux in Children with Persistent Cough and Wheezing <p><strong>Background: </strong>Gastroesophageal reflux (GER) occurs in more than two-thirds of otherwise healthy infants and is the topic of discussion with pediatricians at one-quarter of all routine 6-month infant visits. GER is considered a normal physiologic process that occurs several times a day in healthy infants, children, and adults. GER is generally associated with transient relaxations of the lower esophageal sphincter independent&nbsp; of swallowing, which permits gastric contents to enter the esophagus. The Objective to find out the prevalence of GER in children with cough and wheezing and its associated factors<strong>. Subjects and Methods: </strong>A cross-sectional study was done at A tertiary care hospital at the Institute of Naval Medicine, INHS, Mumbai from August 2016 to December 2017. A total of 30 study subjects Aged between the age of one to twelve years with persistent cough and wheezing lasting for more than three months despite treatment were included for the study<strong>. Results: </strong>The prevalence of gastroesophageal reflux (GER) in our study was 63.3%.The logistic regression analysis showed that Age, Height, Weight, BMI, duration of cough, Duration of asthma were not significantly associated with Gastroesophageal reflux (GER) (p&gt;0.05). <strong>Conclusion: </strong>GER seems to have a high prevalence in children with chronic cough. However, no definite recommendations can be made regarding the management of such cases from our study.</p> Praveen P N, Kushvanth K N, Ashish Mallige Copyright (c) 2020 Author Mon, 28 Dec 2020 00:00:00 +0000