A Study of Clinical and Laboratory profile of Scrub Typhus in a Tertiary care Teaching Hospital

A Study of Clinical and Laboratory profile of Scrub Typhus in a Tertiary care Teaching Hospital

  • Atchuta Chytanya Paka Assistant Professor, Department of General Medicine, NRI Academy of Sciences, Mangalagiri Road, Chinakakani, Guntur, Andhra Pradesh-522503
  • Kamal Rajesh Jampana Associate Professor, Department of General MedicineNimra Institute of Medical Sciences, Nimra Nagar, Ibrahimpatnam, Jupudi, Vijayawada, Andhra Pradesh-521456
Keywords: Clinical symptom & Scrub typhus

Abstract

Background: Scrub typhus, also known as bush typhus, is a disease caused by bacteria called Orienta tsutsugamushi. This ricketssial infection is transmitted to humans through the bite of infected heptombidium mite larvae. Subjects and Methods: All patients were subjected to investigations to establish cause of febrile illness. after complete physical examination routine laboratory investigations like CBC, serology for enteric , malaria, scrub typhus and USG abdomen, chest x-ray ,urine analysis and renal function tests were done in all patients. In all cases diagnosis was based on detection of antibodies using a single step rapid immunochromatography method. Results: 120 patients, who were admitted with undifferentiated acute febrile illness during the study period diagnosed to be suffering from scrub typhus with positive antibodies, the following results were noted. Fever was the most common symptom seen in all the 120 patients (100%). The duration of fever ranging from one to seven days present in 94(78.3%), fever for 7-12days present in 5 (4.2%) patients and more than 2 weeks present in 5 (4.12%) patients. Headache and vomiting symptoms were the commonly associated symptoms. Generalized muscle pain (myalgia) was present in 63(52.5%) patients. Headache was present in 64 (53.3%), diarrohea was complained by 2 patients(1.7%), vomiting in 47(39.2%) patients, shortness of breath was present in 16 (13.3%) patients, abdominal pain was present in 17(14.2%)patients and skin rash was seen in 1 patient(0.8%). Conclusion: Majority of the cases of Scrub typhus are seen in the cooler months of the year and in the rainy season. It has to be considered in the  differential diagnosis of undifferentiated acute febrile illness.

Published
2019-10-29