Comparative Evaluation of Different Dose of Bupivacaine for Pain Control in Cesarean Section
Different Dose of Bupivacaine for Pain Control in Cesarean Section
Background: Spinal anesthesia is the preferred choice of anesthesia for the conduct of emergency and elective cesarean section. Hypotension during spinal anesthesia for caesarean section continues to be a major problem. Aim: The present study investigated the safety and efficacy of 0.25% hyperbaric bupivacaine on the incidence of visceral pain during cesarean section performed under subarachnoid anesthesia. Subjects and Methods: Sixty patients who were scheduled for elective cesarean section, allocated randomly to one of three groups, according to patient`s height. Group 1, 2 and 3 received 3.2-3.6 mL (8-9 mg), 3.6-4.0 mL (9-10 mg) and 4.0-4.4 mL (10-11 mg) of 0.25% hyperbaric bupivacaine, respectively. Results: There was no difference in the incidence of visceral pain between three groups (p>0.05), but the quality of intraoperative analgesia, as needs for general anesthesia was significantly lower in group 3 than groups 1 and 2 (p<0.05). Conclusion: In conclusion, hyperbaric 0.25% bupivacaine in the dose of 10-11 mg is safe and effective in obtaining better quality of block in cesarean section, in order of reducing the severity of visceral pain.