Academia Anesthesiologica International <p><strong class="pull-left">Academia Anesthesiologica International </strong>is a double-blinded peer-reviewed, open access, Bi-annual, online journal that publishes original research articles, review articles, case reports, brief communications and clinical studies in all areas/advances of anesthesia, pain and intensive care. <br><strong>Online ISSN: 2456-7388 | Print ISSN:&nbsp;2617-5479</strong></p> Society for Health Care & Research Development en-US Academia Anesthesiologica International 2617-5479 Comparison of Dexamethasone and Dexmedetomidine as an Adjuvant to 0.375% Ropivacaine in Erector Spinae Plane Block for Lumbar Spine Surgery: A Randomized, Double-Blind, Placebo-Control Trial. <p><strong>Background: </strong>Erector spinae plane block (ESPB) is an interfascial plane block that successfully deposits a local anesthetic deep into the erector spinae muscle that lies adjacent to transverse processes. The present study was conducted to assess the effect of dexmedetomidine and dexamethasone as an adjuvant for the erector spinae plane block (ESPB) to control postoperative pain after lumbar spine surgery. <strong>Subjects &amp; Methods: </strong>60 patients selected for undergoing lumbar spine surgery were divided into 3 groups of 20 each. Group, I patients received 0.375% ropivacaine 20 mL group II patients received 0.375% ropivacaine 20 mL with 8 mg dexamethasone and group III patients received 0.375% ropivacaine 20 mL with 1 <em>µ</em>g/kg dexmedetomidine deep to the erector spinae muscle. Postoperative tramadol consumption, amount of rescue analgesia use, post-surgical hospital stay and postoperative nausea and vomiting (PONV) were recorded. <strong>Results: </strong>The demographic data and intraoperative opioid requirements were comparable in all groups. Postoperative tramadol consumption and rescue analgesic requirement were significantly less in group III as compared to group II and I. Postoperative stay in hospital was 6.1 days in 6.2 days in group II and 4.6 days&nbsp;&nbsp;&nbsp;&nbsp; in group III and the difference was significant. <strong>Conclusion: </strong>Dexmedetomidine is found to be better than dexamethasone as an adjuvant to ropivacaine in erector spinae plane block in lumbar spine surgery.</p> Rakhi Gupta Nishat Nasar Copyright (c) 2021 Author 2021-02-12 2021-02-12 6 1 1 4 A Comparative Study of Epidural Anaesthesia Versus Spinal Anaesthesia for Inguinal Hernioplasty <p><strong>Introduction: </strong>Epidural administration is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord. Spinal anaesthesia is a form of neuraxial regional anaesthesia involving the injection of a local anaesthetic or opioid into the subarachnoid space, generally through a fine needle, usually 9 cm (3.5 in) long. Hernia repair surgery, a single long incision is made in the groin. If the hernia is going down the inguinal canal (indirect), the hernia sac is either pushed back or tied off and removed. <strong>Subjects and Methods: </strong>The study has been conducted in 100 patients posted for elective inguinal hernia repair in the Dept. of Anaesthesia, at tertiary care teaching hospital over a period of six months. Pre anaesthetic evaluation was done along with all requisite blood and urine examination, Hb.BT, CT, ECG, 2D ECHO in pts above 50 yrs. All patients were assessed and they were graded according to the ASA physical status I and II. They were educated regarding the anaesthetic technique. <strong>Result:</strong> Total time taken for performing the procedure was significantly longer with Epidural Anaesthesia than that of Spinal Anaesthesia (8.24 0.32 Vs 4.23 0.52 minutes, p&lt;0.001) but onset of action was comparable in both the groups (7.18 1.18 in Spinal Vs 11.428 0.37 min in Epidural p&lt;0.001 Significant). Intraoperative fluid requirement was statistically higher in Spinal than Epidural (1654 193.2 ml vs 1158.22 78.27.16 ml) (p&lt;0.0001). Duration of Surgery was significantly shorter in Spinal as compared to Epidural (91.24 8.41 vs 126.04 11.32 mins.) (p=0.019). 2 % patients had failure of Epidural block whereas no Spinal Anaesthesia failed in patients.</p> Vivek Vaibhav Copyright (c) 2021 Author 2021-02-12 2021-02-12 6 1 5 11 Comparison of Intrathecal Clonidine and Fentanyl in Hyperbaric Bupivacaine for Spinal Anesthesia and Postoperative Analgesia in Patients Undergoing Lower Abdominal Surgeries <p><strong>Introduction: </strong>Fentanyl and clonidine both prolong sensory and motor block of spinal anaesthesia and duration of postoperative analgesia when used as an adjuvant to intrathecal bupivacaine. Lack of studies that directly compare them regarding their efficacy prompted us to compare both drugs as an adjuvant to intrathecal bupivacaine for spinal anaesthesia and postoperative analgesia in patients undergoing caesarian section<strong>. Subjects and Methods: </strong>It was a prospective randomized study in which eighty patients posted for lower limb orthopedic surgery were divided into two groups of forty each. Group C – Received intrathecal hyperbaric bupivacaine (2.5 ml) +50 <em>µ</em>g clonidine (diluted to 0.5 ml). Group F– Received intrathecal hyperbaric bupivacaine (2.5 ml) + fentanyl 25 <em>µ</em>g (diluted to 0.5 ml). Duration of postoperative analgesia, sensory and motor block characteristics, hemodynamic parameters, and side effects were recorded and analyzed. <strong>Results: </strong>Both the groups were comparable in demographic data, onset and duration of sensory and motor blockade, hemodynamic parameters, but the duration of analgesia is significantly longer in clonidine group when compared with fentanyl group. Sedation score is more in clonidine group. <strong>Conclusion: </strong>Addition of clonidine to intrathecal bupivacaine offers longer duration of postoperative analgesia than fentanyl but with higher sedation.</p> Vivek Vaibhav Copyright (c) 2021 Author 2021-02-12 2021-02-12 6 1 12 16