The Sedation Score (Ramsay Sedation Score) and Recovery Profile (Modified Aldrete’s Score) in Fentanyl, Dexmedetomidineand Placebo Groups

The Sedation Score (Ramsay Sedation Score) and Recovery Profile (Modified Aldrete’s Score) in Fentanyl, Dexmedetomidineand Placebo Groups

  • Liyakhat Ali Assistant Professor, Department of Anesthesiology ,GIMS, Kalaburgi, Karnataka
  • Shrinivas TR Associate Professor, Department of Anesthesiology, KIMS, Koppal, Karnataka
Keywords: The Sedation Score, Recovery Profile, Fentanyl

Abstract

Background: Extubation and emergence from general anesthesia is a stressful event which is a less addressed clinical entity. Problems associated with extubation, recovery, and emergences are more common than problems at intubation. Reports from the UK suggest that respiratory complications are common at extubation and during recovery.  Death or brain injury was more common in claims associated with extubation and recovery than those occurring at the time of induction of anesthesia. Subjects and Methods: The Consolidated Standards of Reporting Trials (CONSORT) recommendations for reporting randomized, control clinical trials were followed.  After obtaining hospital ethics committee approval, a prospective randomized controlled study was done to compare fentanyl, dexmedetomidine and placebo in attenuating of hemodynamic stress response during extubation and emergence from general anaesthesia; in 150 patients with 50 patients in each of 3 groups. Results: Sedation score at 15 min in group A was 1.64±0.56, in group B sedation score was 2.36±0.53. Among group A & B, there was statistically significant difference at 15, 20 and at 120 minutes following extubation (p<0.050). At remaining interval of observation there was no statistically significant difference (p>0.050). Recovery score at 15 min following extubation in group A, B, C were 13.28±0.50, 13.78±0.46, 13.78±0.42 respectively. Conclusion: There was statistically significant difference in recovery score among the groups (p<0.001) at 15, 20, 25 minutes of study period. But clinically recovery score were nearly similar in all 3 groups.

Published
2020-01-10
How to Cite
Liyakhat Ali, & Shrinivas TR. (2020). The Sedation Score (Ramsay Sedation Score) and Recovery Profile (Modified Aldrete’s Score) in Fentanyl, Dexmedetomidineand Placebo Groups. Academia Anesthesiologica International, 4(2), 357-361. Retrieved from http://aijournals.com/index.php/aan/article/view/1316