Assessment of the Level of Abdominal Pain in High- Versus Low-Pressure Carbon Dioxide in Patients Undergoing Laparoscopic Cholecystectomy

Abdominal Pain in High- Versus Low-Pressure Carbon Dioxide in Patients Undergoing Laparoscopic Cholecystectomy

Abstract

Background: To assess the level of abdominal pain in high- versus low-pressure carbon dioxide in patients undergoing laparoscopic cholecystectomy. Subjects and Methods: One hundred twenty adult patients age ranged 18- 48 years of either gender with history of cholecystitis undergoing laparoscopic cholecystectomy were included. Randomization of patients into 2 groups of 60 each was done. Group A comprised of those who underwent pneumoperitoneum with PaCO2 of 710 and group B were those who underwent using PaCO2 of 1214 mm Hg. In both groups, parameters such as abdominal pain at the site of surgery, level of nausea and vomiting and shoulder-tip pain were evaluated. Results: The mean pre- operative and post- operative ALP (u/l) was 168.4 and 148.5, AST was 20.5 and 43.2, ALT (u/l) was 19.2 and 32.7, BILLT (u/l) was 0.60 and 0.67 and BILLD (u/l) was 0.20 and 0.32 in group A respectively. In group B was 184.3 and 187.4, 20.4 and 37.6, 21.3 and 32.5, 0.61 and 0.72 and 0.21 and 0.37 in group B respectively. A significant difference was observed (P< 0.05). There was significant difference in systolic blood pressure and heart beat recorded at 1 hour, 3 hours and 6 hours in group A and B. Conclusion: Low pressure CO2 had benefit over high- pressure CO2 in laparoscopic cholecystectomy.