MRI Evaluation of Response to Percutaneous Sclerotherapy in Slow Flow Vascular Malformations

MRI evaluation to percutaneous sclerotherapy

Abstract

Background: Percutaneous sclerotherapy is an effective treatment for slow flow vascular malformations. Objectives: To evaluate the role of MR imaging in response evaluation after completion of image guided sclerotherapy in patients with slow flow vascular malformation, and to evaluate subsequent symptomatic relief. Subjects and Methods: A cohort observational study of 35 patients was done in our department. After appropriate measures the MRI and Sclerotherapy treatment was done, under ultrasound and fluoroscopy guidance.  After 4 sessions or after complete thrombosis of lesion as seen on ultrasound, MRI was done after 30 days of last session. Statistical Analysis: Data was coded and recorded in MS Excel spreadsheet program. SPSS version 21 has been used for data analysis Mean diameter of lesion in two planes was calculated and reduction in size of lesion was evaluated and classified. Assessment of patients symptom relief was done according to Likert scale. Results & Conclusion: In our study we found that there was no change in size of lesion in 20% cases, minor improvement in 40% cases and major improvement in 40% cases based on reduction in size as evaluated on MRI. The mean Percentage Reduction of Size was 34.23 %. Symptomatic improvement in 8.6% patients was same as before, 48.6% patients had fairly good improvement, 37.1% patients had good improvement and 5.7% patients had very good improvement.