Evaluation of Blood Urea, Serum Creatinine and Cystatin C Levels in Type 2 Diabetic Patients: A Teaching Hospital Based Study

Type 2 Diabetic Patients

Abstract

Background: Type 2 diabetes mellitus is a common and an important cause of morbidity and mortality in both developing and developed countries. Subjects and Methods: 70 subjects were taken according to the exclusion & inclusion criteria, within the age group of 30-65 years and categorized into two groups (A & B). Results: The study group had fasting blood glucose of 139.3 17.05 mg/dL and in the control group, the values were 84.16 7.64 mg/dL respectively. The study group, the mean and standard deviation of blood cystatin C, Blood Urea and creatinine were 1.51 0.32 mg/dL, 29.61 7.54 mg/dL & 0.98 0.23 mg/dL and in the control group; the values were 0.67 0.1 9 mg/dL,  20.4 4.21 mg/dL, 0.80 0.11mg/dL respectively. These findings are similar to a study conducted by Borges et al. Table 1 shows the mean fasting blood sugar, serum cystatin c, blood urea and serum creatinine level was higher among cases when compared with controls and was statistically significant. Conclusion: Serum cystatin C is a significant predictor among patients with type 2 diabetic individuals and that the cystatin C test is more economical and more convenient than the standard method for GFR With the development of medical treatment level. Cystatin C in comparison with serum creatinine can be a useful maker in detecting renal impairment in type 2 diabetic individuals.