Histomorphometric Analysis of Umbilical Arteries in Preeclampsia

Umbilical Artery in Preeclampsia

  • Saleena N Ali Assistant Professor, Department of Anatomy, P K Das Institute of Medical Sciences.
  • Suma H Y Additional Professor, Department of Anatomy, JIPMER.
  • Yogesh Ashok Sontakke Associate Professor, Department of Anatomy, JIPMER.
  • Dilip Kumar Maurya Additional Professor, Department of Obstetrics and Gynaecology, JIPMER.
Keywords: Preeclampsia, Umbilical artery, Luminal area, Diameter

Abstract

Introduction: Preeclampsia is a pregnancy‑related hypertensive disorder complicated with placental hypoxia and resistance. The hypoxia and hypertension can induce changes in the morphometric parameters of umbilical cord and its vessels that can further affect the blood flow to the fetus. Subjects and Methods: Umbilical cords were collected from new-borns of preeclamptic and normal mothers, length and diameter were measured. Further, cords were processed for histological examination. The diameter, luminal area and wall thickness of umbilical arteries were measured. Results: A shorter and narrower cord was observed in preeclampsia. The umbilical arteries in preeclamptic cases were dilated, whereas statistically significant changes were not observed in the thickness of wall. Conclusion: Dilated umbilical arteries would be an adaptation to the affected babies so as to ensure reduced resistance for fetal circulation.

Published
2019-05-06
How to Cite
Ali, S. N., H Y, S., Sontakke, Y., & Maurya, D. (2019). Histomorphometric Analysis of Umbilical Arteries in Preeclampsia. Academia Anatomica International, 5(1), 40-42. Retrieved from https://aijournals.com/index.php/aanat/article/view/609