Assessment of Serum Lipid Profile in Patients Undergoing Cholecystectomy

Abstract

Background: Cholelithiasis is one of the most common gastrointestinal disorders. The present study was conducted to assess lipid profile in patients undergoing cholecystectomy.Subjects and Methods:The present study was conducted on 284 patients of both genders. All patients underwent laproscopic cholecystectomy (LC). Serum concentrations of triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured before and 30 days after the surgery by using specific kit.Results:out of 284 patients, males were 112 and females were 172. Preoperatively total cholesterol increased from 140.2 mg/dl to 172.4 mg/dl, triglyceride decreased from 182.6 mg/dl to 138.5 mg/dl, LDL-C decreased from 76.4 mg/dl to 54.8 mg/dl and HDL-C increased from 42.2 mg/dl to 48.1 mg/dl. The difference was significant (P< 0.05) except HDL-C (P> 0.05).Conclusion: There is alteration of lipid profile in patients undergoing cholecystectomy. Total serum LDL cholesterol and serum triglycerides levels decrease and total serum cholesterol and serum HDL cholesterol increase after cholecystectomy.