Usefulness of CT Scan and MRI for the Detection and Evaluation of Brain Tumors
CT scan and MRI for the Detection and Evaluation of Brain Tumors
Background: Intracranial tumors can arise from various locations in the brain parenchyma. Computed tomography scan (CT) and magnetic resonance imaging (MRI) are important modalities for diagnosis of intracranial tumors. The aim of the study is to study the usefulness of CT scan and MRI for the detection and evaluation of brain tumors. Subjects and Methods: This was a prospective cross sectional study comprising of 95 patients diagnosed with brain tumors clinically. CT scan was done in all the patients and MRI was done in 45 patients. Findings were correlated with histopathology. Results: In the present study, age group distribution included from 20 years to more than 50 years.In the present study males were predominant and the male to female ratio was 1.3:1. All the cases, (100%) presented with seizures, followed by headache, hemiparesis and vomiting. Conclusion: CT scan and MRI imaging modalities are of utmost importance in diagnosing brain tumors. Early diagnosis is important and the imaging guides the neurosurgeon regarding appropriate surgical approach.
Gilman S. Imaging the Brain. N Engl J Med. 1998;338(13):889–896. Available from: https://dx.doi.org/10.1056/nejm199803263381307.
Medina LS, Pinter JD, Zurakowski D, Davis RG, Kuban K, Barnes PD. Children with headache: clinical predictors of surgical space-occupying lesions and the role of neuroimaging. Radiology . 1997;202(3):819–824. Available from: https://doi.org/10.1148/radiology.202.3.9051039.
Medina LS, Pinter JD, Zurakowski D, Davis RG, Kuban K, Barnes PD. Children with headache: clinical predictors of surgical space-occupying lesions and the role of neuroimaging. Radiology. 1997;202(3):819–824. Available from: https://dx.doi.org/10.1148/radiology.202.3.9051039.
Poussaint TY, Gudas T, Barnes PD. Imaging of neuroen- docrine disorders of childhood. Neuroimaging Clin N Am. 1999;9(1):157–75.
Scott JN, Brasher PMA, Sevick RJ, Rewcastle NB, Forsyth PA. How often are nonenhancing supratentorial gliomas malignant? A population study. Neurology. 2002;59:947–949. Available from: https://dx.doi.org/10.1212/wnl.59.6.947.
Saunders W. Single visit endodontics resulted in less pain than multiple visits. Evid Based Dent. 2000;2:12–16. Available from: https://dx.doi.org/10.1038/sj.ebd.6400008.
Silver AJ, Ganti SR, Hilal SK. Computed tomography of tumors involving the atria of the lateral ventricles. Radiology. 1982;145(1):71–78. Available from: https://dx.doi.org/10.1148/radiology.145.1.7122900.
Dandy WE. Ventriculography Following the Injection of Air into the Cerebral Ventricles. Ann Surg. 1918;68(1):5–11. Available from: https://dx.doi.org/10.1097/00000658-191807000-00002.
Lee YY, Tassel PV, Bruner JM, Moser RP, Share JC. Juvenile pilocytic astrocytomas: CT and MR characteristics. Am J Roentgenol. 1989;152(6):1263–1270. Available from: https://dx.doi.org/10.2214/ajr.152.6.1263.
Saleem SN, Said AHM, Lee DH. Lesions of the Hypotha- lamus: MR Imaging Diagnostic Features. Radiographics. 2007;27:1087–1108. Available from: https://dx.doi.org/10.1148/rg.274065123.
van Dijke CF, Brasch RC, Roberts TP, Weidner N, Mathur A, Shames DM. Mammary carcinoma model: correlation of macromolecular contrast-enhanced MR imaging characteriza- tions of tumor microvasculature and histologic capillary den- sity. Radiology. 1996;198(3):813–818. Available from: https://dx.doi.org/10.1148/radiology.198.3.8628876.
Schwickert HC, Stiskal M, Roberts TP, van Dijke CF, Mann J, Mühler A. Contrast-enhanced MR imaging assessment of tumor capillary permeability: effect of irradiation on delivery of chemotherapy. Radiology. 1996;198(3):893–898. Available from: https://dx.doi.org/10.1148/radiology.198.3.8628889.
Roberts HC, Roberts TP, Brasch RC, Dillon WP. Quantita- tive estimation of microvascular permeability in human brain tumors using dynamic contrast-enhanced MR imaging: correla- tion with histological grade. Am J Neuroradiol. 2000;21:891– 899.
Roberts HC, Roberts TPL, Bollen AW, Ley S, Brasch RC, Dillon WP. Correlation of Microvascular Permeability Derived from Dynamic Contrast-Enhanced MR Imaging with Histologic Grade and Tumor Labeling Index. Acad Radiol. 2001;8(5):384–391. Available from: https://dx.doi.org/10.1016/s1076-6332(03)80545-7.
Sole AD, Falini A, Ravasi L, Ottobrini L, Marchis DD, Bom- bardieri E. Anatomical and biochemical investigation of pri- mary brain tumours. Eur J Nucl Med. 2001;28(12):1851–1872. Available from: https://dx.doi.org/10.1007/s002590100604.
Sannazzari GL, Ragona R, Redda MGR, Giglioli FR, Isolato G, Guarneri A. CT–MRI image fusion for delineation of volumes in three-dimensional conformal radiation therapy in the treatment of localized prostate cancer. Br J Radiol. 2002;75(895):603–607. Available from: https://dx.doi.org/10.1259/bjr.75.895.750603.
Rajasekar D, Datta NR, Gupta RK, Pradhan PK, Ayyagari S. Multimodality image fusion in dose escalation studies of brain tumors. J Appl Clin Med Phys. 2003;4(1):8–16. Available from: https://dx.doi.org/10.1120/jacmp.v4i1.2545.
Metcalfe P, Liney GP, Holloway L, Walker A, Barton M, Delaney GP, et al. The Potential for an Enhanced Role for MRI in Radiation-therapy Treatment Planning. Technol Cancer Res Treat. 2013;12(5):429–446. Available from: https://dx.doi.org/10.7785/tcrt.2012.500342.
Taghipour Z, Sadrabadi RM, Dehghani F. Evaluation of Diagnostic Value of CT Scan and MRI in Brain Tumors and Comparison with Biopsy. Iran J Ped Hematol Oncol. 2011;1(4):121–125.
Ubhale B, Shah H, Shah J. Demographic and histopathologic profile of pediatric brain tumors: A hospital-based study. South Asian J Cancer. 2015;4(3):146–146. Available from: https://dx.doi.org/10.4103/2278-330x.173165.
Ahmad MS, Anjum R, Singh A, Singh DK, G DKD. EVAL- UATION OF BRAIN TUMOURS BY MRI TECHNIQUES AND THEIR HISTOPATHOLOGICAL CORRELATION. J Evol Med Dent Sci. 2014;3(70):14971–14984. Available from: https://dx.doi.org/10.14260/jemds/2014/4013.
Prabhakar R, Haresh KP, Ganesh T, Joshi RC, Julka PK, Rath GK. Comparison of computed tomography and magnetic resonance based target volume in brain tumors. J Cancer Res Ther. 2007;3(2):121–121. Available from: https://dx.doi.org/10.4103/0973-1482.34694.
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