Lung Manifestation of Collagen Vascular Disease in HRCT

Lung Manifestation of Collagen Vascular Disease in HRCT

  • Jagruti Kalola Additional Professor, Department of Radio diagnosis PDU Medical College& Government Hospital, Rajkot
  • Anjana Trivedi Professor and Head, Department of Radio diagnosis PDU Medical College& Government Hospital, Rajkot
  • Hiral Happani Assistant Professor, Department of Radio diagnosis PDU Medical College & Government Hospital, Rajkot
  • Mohit Chauhan Resident Doctor, Department of Radio diagnosis PDU Medical College& Government Hospital, Rajkot


Background: The aim of this paper was to evaluate the thoracic manifestations associated with the Connective tissue disorders, with an emphasis on interstitial and airway disease pattern on the High Resolution computed tomography (HRCT) findings. Subjects and Methods: The present study was conducted for a period of one year. A total of 50 patients with various connective tissue disorders having respiratory complaints were evaluated. Results:  During the study period 50 patients (80%females and 20%males) underwent evaluation. Cough and dyspnea were  the most common presenting symptoms. Variety of thoracic abnormalities weredetected in 67 (95%) cases. Most common abnormality detected on HRCT was interstitial fibrosis/interstitial lung disease present in (60%) cases. Most common parenchymal abnormalities seen were reticulations (61.4%), ground glass opacification (40%), mosaic attenuation (32.8%) and honeycombing (24.3%). Airway abnormalities seen were bronchiectasis (48.5%), emphysema (12.8%), and ground glass nodules (2.8%). Conclusion: Interstitial lung disease is the most common pulmonary manifestation among patients with connective tissue disorders, and early detection and prompt treatment is expected to improve the outcome.


Download data is not yet available.


Bouros D, Pneumatikos I, Tzouvelekis A. Pleural Involve- ment in Systemic Autoimmune Disorders. Respiration. 2008;75(4):361–371. Available from:

Woodhead F, Wells AU, Desai SR. Pulmonary Compli- cations of Connective Tissue Diseases. Clin Chest Med. 2008;29(1):149–164. Available from:

Mayberry JP, Primack SL, Müller NL. Thoracic Man- ifestations of Systemic Autoimmune Diseases: Radio- graphic and High-Resolution CT Findings. Radio- Graphics. 2000;20(6):1623–1635. Available from:

Afeltra A, Zennaro D, Garzia P, Gigante A, Vadacca M, Ruggiero A, et al. Prevalence of interstitial lung involvement in patients with connective tissue diseases assessed with high-resolution computed tomography. Scand J Rheumatol. 2006;35(5):388–394. Available from:

Noor NM, Shahrir MSM, Shahid MS, Manap RA, Azura AMS, Shah SA. Clinical and high resolution computed tomography characteristics of patients with rheumatoid arthritis lung disease. Int J Rheum Dis. 2009;12(2):136–144. Available from:

Zrour SH, Touzi M, Bejia I, Golli M, Rouatbi N, Sakly N. Correlations between high-resolution computed tomography of the chest and clinical function in patients with rheumatoid arthritis. Prospective study in 75 patients. Joint Bone Spine. 2005;72(1):41–48. Available from:

Fenlon HM, Doran M, Sant SM, Breatnach E. High-resolution chest CT in systemic lupus erythematosus. Am J Roentgenol. 1996;166(2):301–307. Available from:

Goldin JG, Lynch DA, Strollo DC, Suh RD, Schraufnagel DE, Clements PJ, et al. High-Resolution CT Scan Findings in Patients With Symptomatic Scleroderma-Related Interstitial Lung Disease. Chest. 2008;134(2):358–367. Available from:

Ikezoe J, Johkoh T, Kohno N, Takeuchi N, Ichikado K, Nakamura H. High-Resolution CT Findings of Lung Disease in Patients with Polymyositis and Dermatomyositis. J Thorac Imaging. 1996;11(4):250–259. Available from:

Koyama M, Johkoh T, Honda O, Mihara N, Kozuka T, Tomiyama N. Pulmonary involvement in primary Sjögren’s syndrome: spectrum of pulmonary abnormalities and computed tomography findings in 60 patients. J Thorac Imaging. 2001;16(4):290–296. Available from:

How to Cite
Jagruti Kalola, Trivedi, A., Happani, H., & Chauhan, M. (2020). Lung Manifestation of Collagen Vascular Disease in HRCT. Asian Journal of Medical Radiological Research, 8(1), 9-13.