New Generation Contrast Media and Renal Saftey

Abstract

Background: With the advancement in radiological interventions and diagnostic imaging iodinated contrast has an important role to play. Research and advancement in contrast media safety makes this pharmaceutical agent safe to use in daily practice. Our study is done to assess the safety of present generation iodinated contrast media over the kidneys in patients with heterogenous clinical setting undergoing contrast enhanced CT with serum creatinine and e-GFR as a tool for renal function assessment. The study concludes low-osmolar non ionic contrast is safe in general population; however, we would advise judicious use of intravenous low-osmolar non-ionic contrast in patients with associated comorbid conditions due to mild but insignificant rise in serum creatinine values.Subjects and Methods: Prospective study done with 158 patients undergone computed tomography with Low-osmolar non-ionic iodinated contrast media. Sr,creatinine and eGFR are obtained.Results:Age of the patient does not have direct influence on percentage of creatinine variation where ascormorbidconditions of the patient has.Conclusion: Incidence of contrast induced nephropathy among the general population is negligible however judicious use of contrast media is necessary in patients with cormorbid conditions.