Academia Journal of Medicine http://aijournals.com/index.php/ajm <p style="text-align: justify;"><strong>Academia Journal of Medicine (AJM)</strong> is an open-access; freely accessible, online and print Bi-Annual peer-reviewed international journal publishes a wide spectrum of advanced research in different fields of clinical medicine, covering etiology, diagnosis, therapy and prognosis aspects.<br> <strong>Online ISSN: 2663-8290 | Print ISSN: 2663-8282</strong></p> en-US dir.journals@gmail.com (Dr. Rohit Varshney) dir.journals@gmail.com (Dr. Rohit Varshney) Wed, 24 Jul 2019 18:26:35 +0000 OJS 3.1.2.1 http://blogs.law.harvard.edu/tech/rss 60 Clinical Profile of TB Patients on DOTS at a Tertiary Care Hospital http://aijournals.com/index.php/ajm/article/view/839 <p><strong>Background: </strong>Tuberculosis was considered to be among the top ten causes of global mortality and morbidity. The highest incidence of TB was found in developing countries. Estimates suggest that 32% of the world‟s population was infected with TB. In India, it was seen that TB kills more adults than any other infectious disease. 20% global burden of TB was in India.<strong> Subjects and Methods: </strong>Before initiating anti-tuberculosis treatment a detailed clinical assessment which included history and clinical examination was done. Hematological investigations like HIV test is done as per ICTC along with HBsAg. Hematological investigations included hemoglobin, WBC count, differential count, platelet count, prothrombin time and ESR. Biochemical investigations included total bilirubin, direct bilirubin, AST, ALT, alkaline phosphatase, random blood sugar, blood urea, s.creatinine and uric acid. <strong>Results: </strong>Out of the 50 patients studied, 70 % patients were sputum positive and 30 % were sputum negative. This is probably because majority of the patients studied were pulmonary tuberculosis. <strong>Conclusion: </strong>Adverse drug reaction was seen in 29 patients (58 %). One or more types of ADR was seen in these patients.</p> Arjun H, Santosh VG Copyright (c) 2019 Academia Journal of Medicine http://aijournals.com/index.php/ajm/article/view/839 Wed, 24 Jul 2019 00:00:00 +0000 Clinical Profile of Snake Bite Envenomation in Patients Admitted at Tertiary Care Hospital http://aijournals.com/index.php/ajm/article/view/881 <p><strong>Background: </strong>Snakebite envenoming is a potentially life-threatening disease that typically results from the injection of venom following the bite of a venomous snake. Sometimes envenoming can also be caused by venom being sprayed into a person’s eyes by certain species of snakes that have the ability to spit venom as a defense measure. Not all snakebites are venomous. Some snakes are non-venomous and venomous snakes do not always inject venom during a bite. <strong>Subjects and Methods: </strong>Patients were examined for complications of snake bite. Haemotoxicity was assessed based on features like bleeding from the bite site, gums, epistaxis, haemoptysis, haematemesis, rectal bleeding or malaena, haematuria, vaginal bleeding, bleeding into the mucosae, skin (petechiae, purpura, discoid haemorrhages, ecchymoses. Neurotoxicity by drowsiness, paraesthesiae, abnormalities of taste and smell, ptosis, external ophthalmoplegia, paralysis of facial muscles and other muscles innervated by the cranial nerves, respiratory and generalized flaccid paralysis. <strong>Results: </strong>Majority of the patients were farmers with 44% followed by housewives (26%). Lower limbs were the most common site of bite in our study group comprising of74% of the patients. <strong>Conclusion: </strong>Most common manifestation of envenomation is local envenomation comprising of 66%.</p> N. Kotresh, V. Sunitha Copyright (c) 2019 Academia Journal of Medicine http://aijournals.com/index.php/ajm/article/view/881 Tue, 13 Aug 2019 00:00:00 +0000 To Assess Correlation of Fasting Blood Glucose, Hb1Ac and Serum Lipid Level in Type II Diabetes Mellitus Patients http://aijournals.com/index.php/ajm/article/view/914 <p><strong>Background: </strong>Diabetes Mellitus (DM) refers to a group of common metabolic disorder that share the phenotype of hyperglycaemia caused due to either deficiency of insulin secretion or insulin resistance. The present study was conducted to assess correlation of fasting blood glucose, Hb1Ac and type II DM in given adults. <strong>Subjects and Methods: </strong>The present study was conducted on 134 patients with type II diabetes mellitus (DM) of both genders. Patients were subjected to estimation of fasting and random blood glucose level. Modified method of Fluckiger and Winterhalter was used for estimation of glycosylated haemoglobin (HbA1C). <strong>Results: </strong>Out of 134 patients, males were 84 and females were 50. Age group 20-30 years had 11, 30-40 years had 14, 40-50 years had 38, 50-60 years had 46 and &gt;60 years had 25 patients. The mean fasting blood glucose level in patients with good degree of control was 106.2, in fair was 164.4 and in poor was 208.2. Glycosylated hemoglobin level was good (6.74), fair (8.12) and poor (12.54). A positive correlation of fasting blood glucose and glycosylated hemoglobin level and serum cholesterol &amp; glycosylated hemoglobin level (P&lt; 0.05) was found. <strong>Conclusion: </strong>Authors found a positive correlation of fasting blood glucose and glycosylated hemoglobin level and serum cholesterol &amp; glycosylated hemoglobin level in type II diabetes mellitus patients</p> Nagendra Singh Chauhan, Hemendra Kumar Agrawal Copyright (c) 2019 Academia Journal of Medicine http://aijournals.com/index.php/ajm/article/view/914 Thu, 15 Aug 2019 00:00:00 +0000 A Hospital Based Cross-sectional Study on Demographic Distribution of Both Symptomatic and Asymptomatic Patients an Art at Westren Region of Rajasthan. http://aijournals.com/index.php/ajm/article/view/1002 <p><strong>Background: </strong>Over the past two decades with the advent of highly active antiretroviral therapy (HAART), there is a substantial increase in the life span of HIV patients. Morbidity and mortality due to human immunodeficiency virus (HIV) continue to be major problems in developing countries like India. <strong>Subjects and Methods: </strong>The present study was a cross sectional hospital based study for a period of twelve months from 1st Nov. 2015 to 31st Oct. 2016 at ART center P.B.M. Hospital, Bikaner. 100 HIV+ patients on ART were included in the study by consecutive sampling technique. <strong>Results: </strong>We found that Maximum number of study participants in age group of 31-40 years in both study (50%) and control (42%) group. Males were higher in study (76%) as well as control (64%) group than females .Among the subjects mostly belonged to lower socioeconomic status followed by Medium and High socioeconomic status. Most of the subjects in study (92%) as well as control (94%) groups were married. <strong>Conclusion: </strong>We conclude that Males were higher in study (76%) as well as control (64%) group than females .Among the subjects mostly belonged to lower socioeconomic status followed by Medium and High socioeconomic status.</p> <p>&nbsp;</p> Alok Gahlot, Pooja Gahlot, Jitendra Acharya Copyright (c) 2019 Academia Journal of Medicine http://aijournals.com/index.php/ajm/article/view/1002 Tue, 08 Oct 2019 00:00:00 +0000 A Cross Sectional Study on Correlation of Quantitative C - reactive protein With CD4 Count in Patients of HIV on Art http://aijournals.com/index.php/ajm/article/view/1003 <p><strong>Background: </strong>Over the past two decades with the advent of highly active antiretroviral therapy (HAART), there is a substantial increase in the life span of HIV patients. Hence, the focus has now shifted to managing long-term complications of HIV infection and improving the quality of life of HIV patients, especially in developed nations. On the other hand, in developing nations, the ever-growing incidence of HIV infection has placed a huge burden on their frail economy, so there is a growing need for simplifying HIV treatment protocols and for having cheaper alternatives for monitoring disease activity. <strong>Subjects and Methods: </strong>The present study was a cross sectional hospital based study for a period of twelve months from 1st Nov. 2015 to 31st Oct. 2016 at ART center P.B.M. Hospital, Bikaner. 100 HIV+ patients on ART were included in the study by consecutive sampling technique. Out of 100 patients, 50 were symptomatic and included in study group and remaining 50 were asymptomatic and taken as controls. <strong>Results: </strong>37 (74%) patients in study group had CRP levels &gt;6 mg/lit (normal level &lt;6 mg/lit). Out of 37, 19 subjects (38% of total) had CRP level &gt;20 mg/lit. While in control group, 44 subjects (88%) had CRP level &lt;6 mg/lit.&nbsp; Only 6 (12%) subjects of control group had CRP level &gt;6mg/lit. None of control subjects had CRP level &gt;20 mg/lit. The CRP levels and CD4 count were negatively correlated in study group and this was observed to be statistically significant (p=0.04) whereas in control group, the CRP levels and CD4 counts were found to be very weakly positively correlated and this correlation was observed to be statistically insignificant. <strong>Conclusion: </strong>There was statistical significant difference between CRP range and levels in both the groups. Also statistical significant difference between CD4 count range in both the groups.&nbsp; In our study, 38% of the study group patients had CRP &gt;20 mg/l whereas 88% of the control subjects had CRP of &lt;6 mg/l.</p> Alok Gahlot, Pooja Gahlot, Jitendra Acharya Copyright (c) 2019 Academia Journal of Medicine http://aijournals.com/index.php/ajm/article/view/1003 Wed, 09 Oct 2019 00:00:00 +0000